What percentage of peripheral cells do neutrophils make up?
60-70%
T/F: Neutrophils cannot kill bacteria
False
Only 2-3% of these cells can phagocytize and kill bacteria.
Eosinophils
Compared to neutrophils, eosinophils live ________.
longer
Red granules
Eosinophils
Two loves of a single nucleus and are seen in allergies and parasites.
Eosinophils
Cells of inflammation in tissue.
Macrophages.
Macrophages in the blood.
Monocytes
Macrophages in the spleen.
Litteral cells.
Secrete cytokines and make complement factors.
Macrophages
Macrophage life-spans are _________.
long
6 Cells of inflammation
Neutrophils, eosinophils, basophils, macrophages, platelets, and lymphocytes
Fragments of cytoplasm from megakaryoctyes in bone marrow
Platelets
Produce many humeral mediators of inflammation
Platelets
2 humeral mediators of inflammation released by platelets.
histamine cyokine and growth factors
3 ways to classify inflammation
Duration, Etiology, and Locations
Name 4 things etiology deals with.
infectious agents, physical, chemical and immune factors
What is a furuncle?
A localized skin infection
Is Bryan dumb?
Yes.
skin vesicles?
serous inflamation
fibrin and cells leak-fibrinous pericarditis?
fibrinous inflammation
Associated with pus-forming bacteria such as staph and strep- can lead to abscess and healing with granulation tissue
Purulent inflammation
defect in epithelium?
ulcerative inflammation
exudates of fibrin-seen in colon in C. difficile infections?
pseudo membranous inflammation
collections of macrophages produce granulomas- seen in TB and histoplasmosis?
granulomatosus inflammation
tissue seen in reparative processes with new blood vessels, new collagen formation and mononuclear cells?
granulation tissue
Symptoms related with this pathology? fever, pain, leukocytosis- release cytokines IL-1 adn tissue necrosis factor- acto on the hypothalamus-release of prostaglandins
Acute appendicitis
In wound healing (skin incisions), what cells play a role?
1.
2.
3.
4.
1. leukocytes
2. macrophages
3. connective tissue
4. epithelial cells
Why do sprained ankles stay swollen for a long time?
new vessel formation leak for awhile
Fibroblasts produce __________ and ___________, first type III ad then to type I.
1. fibronectin
2. collagen
The vascularized connective tissue that is rich in macrophages, myofibroblasts, angioblasts and fibroblasts is called ___________?
Granulation Tissue
7 factors that affect healing?
site of wound, mechanical factors, size of wound, presence or absence of infection, circulatory status, nutritional and metabolic factors, age
