EENT-Derm plus pharm

• Therapeutic class: antifungal
• Preg cat: C
• MOA: Binds to membrane sterols in fungal cell causing leakage-kill son contact
• Indications: Topical fungal infections or oral fungal infections. depending on infection route may differ.
• Contraindications: hypersensitivity
• Adverse: skin irritation

• Therapeutic class: Antifungal
• Preg: B 
• MOA: Binds to membrane sterols in fungal cell causing leakage-kills on contact
• Indications: effective against a wide range of fungi
• Contraindications: hypersensitivity 
• Adverse: N/V, fever, chills, headache, nephrotoxicity
• Alerts: Infuse slowly IV, hold for elevated BUN or creatinine.
• Interactions: Many

• Therapeutic class: Antiparasitic
• Preg: B
• MOA: Affects the nervous system of parasite causing paralysis, they did in 24-48 hours because they're unable to feed.
• Indications: scabies, parasites
• Contraindications: Hypersensitivity 
• Adverse: itching, burning, rash, redness, edema
• Alert: Caution with asthma, lactating or inflamed skin. Wear gloves-for lice-medications should remain on on head for 10 mins. Itching may persist for up to 2-3 weeks. Avoid Face and groin
• 1% for Lice
• 5% for scabies

• Therapeutic class: antibacterial
• Preg: C
• MOA: Bacteriostatic: Interferes with bacterial cell-wall synthesis and metabolism– Effective against gram negative organisms
• Indications: topical water soluble antibacterial agent in 2nd and 3rd degree burns.
• Contraindications: hypersensitivity
• Adverse: metabolic acidosis, respiratory alkalosis, blistering, superinfections. Life threatening reactions-Bone marrow suppression, fatal hemolytic anemia. 
• Alert: Assess electrolytes and acid-base balance-BUN/creatinine

• Therapeutic class: Antiacne
• Preg: X
• MOA: decreases sebum production, causes apoptosis in sebaceous glands as well as others. 
• Indications: decrease sebum production, severe acne with cysts.
• Contraindications: Pregnancy, sunburns, eczema, children under 12, hepatic disease, leukopenia, neutropenia
• Adverse: Bone pain–, Fever, –Headache,– Nausea–, Vomiting, –Rash–, Stomatitis, –Pruritus–, Sweating –Ocular disorders 25% of patients develop retinoic acid syndrome (–Fever, Weakness, Fatigue, Edema, Pulmonary involvement)
• Alert: occuations with prolonged sun exposure.

• Therapeutic class: antiacne
• Preg: C
• MOA: Carboxylic acid form of vitamin A-for skin turnover.
• Indications: Acne
• Contraindications: 
• Adverse: Increased sensitivity to sunlight, –Redness–, Scaling erythema, –Crusting and peeling of skin

• Therapeutic class: parasympathomimetic 
• Preg: C
• MOA: muscarinic receptor agonist in PNS-causing contraction of iris sphincter muscles allowing an increase of aqueous outflow
• Indications: open and closed angle glaucoma
• Contraindications: narrow-angle glaucoma, hypersensitivity, pupillary block glaucoma, uncontrolled asthma,
• Adverse: Dyspnea–, Hypertension–, Tachycardia–, Retinal detachment–, Bronchospasm [long term use]
• Antidote: Atropine
• Alert: Apply pressure to lacrimal ducts in order to prevent systemic effects.

Dilation of pupils-cycloplegics-used for eye exams. not use for patient with glaucoma due to potential for glaucoma attack.

Constriction

• Is a non selective beta 1 and beta 2 adrenergic receptor blocking agent which reduces vasodilation.  decreases cardiac output and also causes a decrease in aqueous humor and an increase in outflow. 
• Decreasing production of aqueous-decreasing intraocular pressure. used for open angle glaucoma, ocular hypertension, migraines, HTN. 
• adverse effects: Bronchoconstriction( caution with asthma patients), dysrhythmias, hypotension, burning
• Alert: remain immobile for 5 minutes before driving.

• believed to reduce intraocular pressure by increasing the outflow of aqueous humor.
• dilates trabecular meshwork.Used for ocular hypertension and open angle glaucoma.

• increased Intraocular pressure.
• if left untreated leads to optic nerve damage

is an otic solution containing antipyrine, benzocaine, and dehydrated glycerin.

• inflammation behind the tympanic membrane-with accumulation of fluids. viral or bacterial
• 48-72 hours is watchful waiting for children 2 years and older due to most being viral.
• Can cause conductive hearing loss later in life.

Cataracts.