Mesangial cells are contractile and helpregulate glomerular filtration.
What is the purpose of podocytes and where and they located?
The Glomerular (Bowman’s) Capsule has avisceral layer of podocytes which wraparound the capillaries. Podocytes form pedicels, between which arefiltration slits.
What is the macula densa?
The ascending loop contacts the afferentarteriole at the macula densa.
What are juxtamedullary cells?
The wall of the arteriole contains smooth muscle cells; juxtaglomerular cells.
What are principal cells?
principal cells are receptors for ADH and aldosterone
what are intercalated cells?
intercalated cells help to manageblood pH
Which nephrons enable the body to produce very concentrated urine?
juxtamedullary nephrons
which type of nephrons are the most abundant?
cortical
how much filtrate produce by glomerular capsule each day?
150-180L.
What causes afferent arterioles to the glomerular capsule to constrict?
High GFR diminishes reabsorption. Macula Densa inhibits the release of nitric oxide (which causes vasodilation) and afferent arterioles constrict
what effect does angiotensin II have on GFR?
Angiotensin II constricts afferents andefferents, diminishing GFR.
What is the pressure in the glomerular capillaries known as?
The glomerular hydrostatic pressure is the blood pressure in the glomerular capillaries. The pressure tends to push water and solute molecules out of the plasma and into the filtrate.
What does NHP stand for and what does it mean?
NHP stands for net filtration pressure. The net filtration pressure is the difference between the glomerular hydrostatic pressure and the capsular hydrostatic pressure.
What is the osmotic pressure resulting from the presence of suspended proteins in the blood?
blood colloid osmotic pressure
How is the net filtration pressure calculated?
The NFP is calculated by the difference between the net hydrostatic pressure and the blood colloid osmotic pressure
