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ibuprofin, indomethacin, Aleve, Relafen, Toradol
NSAIDS
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celecoxib, Celebrex, allupurinol
COX-2 inhibitors
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colchicine, probenecid
Gout Medications
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Oxycodone and aspirin
Percocet
percodan
empirin #3
Tylenol 3
Vicodin
Opioid/ Non-Opioid Combination Drugs
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TNF inhibitors
Gold Salts
minocycline
antimalarial agents
DMARDS
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What are DMARDS?
- Disease Modifying Anti-Rheumatic Drugs
- TNF inhibitors suppress the immune system by blocking the activity of TNF- Tumor Necrosis Factor (a substance in the body that causes inflammation)
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Enzyme that breaks down arachidonic acid into prostiglandins which have potent inflammatory properties
Cyclo- oxygenase
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Natural or synthetic morphine like substance used for reducing pain
Opioid
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Anti- Gout medication
probenicid
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Narcotic antagonist used to reverse effects of Opioids
naloxonehydrochlorine (Narcan)
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Opioid mechanism of action
interact with binding sites (opiate receptors) in the CNS
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Enzyme produced only during inflammation
COX- 2
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SELECTIVELY inhibit COX-2
Celebrex and NSAIDs
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NSAIDs mechanism of action
inhibits prostaglandin synthesis by inhibiting the cyclooxygenase enzymes resulting in reduction of inflammation
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Synthetic opioid analgesic that alters the perception of and emotional response to pain
oxycodone (Oxycontin)
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NSAID stands for...
Non Steroidal Anti Inflammatory drug that relieve pain and reduces inflammation; also has some anti-platelet and anti-pyretic effects
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COX-1
protective enzyme that protects the gastric mucosa and maintains normal platelet function
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