Basic Bio-pharmaceutics

the location where an administered drug products an effect

the cellular material located at the site of action that interacts with the drugs

the characteristic of drug that makes its action specific to certain receptors and tissues

drugs that activate receptors to accelerate or slow normal cellular function

drugs that bind with receptors but do not activate them. they block receptor action by preventing other drugs or substances from activating them.

the study of the factors associated with drug products and physiological processes and the resulting systematic concentration of drugs

the blood concentration needed for a drug to produce a response

the time MEC is reached and response occurs

a drug's blood concentration range between MEC and MTC

the upper limit of the therapeutic window. drug conentrations above the MTC increase risk of undesired effects.

the time drug concentration is above MEC

a term sometimes used to refer to all of the ADME processes together

the processes of metabolism and excretion

the movement of drugs from an area of higher concentration to lower concentration

fat-like substance

water repelling; cannot associate with water

capable of associating with or absorbing water

the movement of drugs from an area of lower concentration to an area of higher concentration. cellular energy is required.

the movement of a drug from a dosage formulation to the blood

the time a drug will stay in the stomach before it is emptied into the small intestine

the attachment of a drug molecule to a plasma or tissue protein, effectively making the drug inactive but also keeoing it within the body

when different molecules associate or attach to each other

the substance resulting from the body's transformation of an administered drug

a complex protein that catalyzes chemical reactions

the increase in hepatic enzyme activity that results in greater metabolism of drugs

the decrease in hepatic enzyme activity that results in reduced metabolism of drugs

the transfer of drugs and their metabolites from the liver to the bile in the gallbladder then into the intestine and then back into circulation

the substantial degradation of an orally administered drug caused by enzyme metabolism in the liver before the drug reaches the systematic circulation

the functional unit of the kidneys

the blood filtering process of the nephron

drug products that contain identical amounts of the same active ingredient in the same dosages form

drug products that contain the same active ingredient but not necessarily in the same salt form amount or dosage form

pharmaceutical equivalents that produce the same effects in patients

the relative amount of an administered dose that reaches the general circulation and the rate at which this occurs

the comparison of bioavailibilty between two dosage forms