elongated contractile cells; moderate amounts of ECM
characteristics of connective tissue
several types of fixed and motile cells; extensive ECM
parenchyma
tissue compose of the cells responsible for the main functions of an organ
stroma
supporting tissue
principle functions of epithelial tissue
covering, lining, & protection; absorption;
secretion; contractility
lamina propria
found outside the basal lamina in the epithelial layers of internal organs; the layer of connective tissue on which epithelial tissue rests; supports epithelium and binds to underlying layers
papillae
small evaginations that increase the area of contact between the lamina propria and the epithelium; most common in areas subject to high friction
basal pole of epithelial cell
the side of the epithelial cell that faces toward the connective tissue
apical pole of epithelial cell
the side of the epithelia opposite the basal pole
lateral sides of epithelial cell
intervening sides of an epithelial cell that lie apposed to other cells
basal lamina
a sheet of felt-like material that lies at the base of epithelial cells
lamina densa
the electron-dense layer of the basal lamina; made up of network fibrils
dense layer
another name for the lamina densa
laminae lucida
"""clear layers"" sometimes found on either side of the lamina densa; part of the basal lamina"
clear layers
another name for the laminae lucida
basement membrane
formed by the combination of a basal lamina and a reticular lamina; visible under a light microscope
occluding junction
a type of intercellular junction that serves to prevent the flow of material between cells; found at the most apical part of the cell
adherent junction
a type of intercellular junction that serves to adhere cells to each other; encircles the cell; mediated by cadherins; involves actin
gap junction
a type of intercellular junction that allows for communication between cells; mediated by connexons
tight junctions
also known as zona occludens; occluding junctions
zona occludens
also known as tight junctions; occluding junctions
cadherins
transmembrane glycoproteins that enable adhesion between cells in the presence of calcium
zona adherens
also known as adherent junction
hemidesmosomes
adhesive structures that bind the epithelial cell to the basal lamina; resemble half of a desmosome except that they contain integrins instead of cadherins as adhesive proteins
desmosome
"a type of intercellular junction that serves to adhere cells to each other; does NOT encircle the cell; disk-shaped; utilizes cadherins
macula adherens
also known as a desmosome
connexins
dumbell-shaped protein subunits of connexons; six connexins form a connexon
connexons
abutting particles of a gap junction; composed of connexins
microvilli
actin-based, non-motile cellular protrusions that increase the surface area of a cell
stereocilia
actin-based, non-motile cellular protrusions; similar to microvilli but larger; differ from actual cilia in their composition and lack of motility
cilia
motile cellular protrusions; powered by dynein or other motor proteins; composed of microtubules; larger than microvilli; propel fluid
simple epithelia
contain only one layer of cells
stratified epithelia
contain more than one layer of cells
simple columnular epithelia
epithelial cells that are taller than they are wide; have oblong nuclei; involved in absorption and processing
simple cuboidal epithelia
epithelial cells that are roughly as tall as they are wide; have circular nuclei; often have many mitochondria for active transport; usually involved in secretion and absorption
pseudostratified columnular epithelia
simple epithelial cells that appear stratified due to nuclei of different heights; almost exclusively found in the large airways of the respiratory tract
stratified squamous epithelia
line moist tissues that are subject to abrasion
stratified cuboidal epithelia
found in sweat and salivary glands; provides a lining that is more robust than simple stratified epithelium; involved in protection and secretion
transitional epithelia
"found in the mammalian urinary tract; characterized by dome-like ""umbrella"" cells; protect against potentially cytotoxic effects of urine"
stratified squamous keratinized epithelia
found in skin; provides a barrier to abrasion and dessication
terminal web
a cytoskeletal element composed of actin filaments; found at the apical side of the cell
simple squamous epithelia
thin, flat layer of epithelial cells; typically line vessels and cavities; usually involved in selective diffusion