Mcb165 lec 17

The flashcards below were created by user Anonymous on FreezingBlue Flashcards.

  1. _____ declines during normal aging
    Cognitive
  2. What types of cognitive fxns are maintain during aging?
    • Knowledge of vocabulary/ verbal memory¬†
    • Image Upload 1
  3. What happens to the brain volume with normal age?
    • Brain shrinks, due to loss of neurons, but more loss of myelin, dendrites and synapses
    • Image Upload 2
  4. What is the physiology as aging occurs at a synaptic level?
    Fewer dendritic spines and branches. NMJs are not well fxning and losing connectivity between pre and post synapses.
  5. What does caloric restriction do to the physiology of NMJs?
    • Helps repair/ rescue the non-fxnlity of synapse, seeing more nervation and sprouting than the old control mice¬†
    • Image Upload 3
  6. What happens to synaptic plasticity in older animals ?
    Synaptic plasticity, using pair-pulsed facilitation and depression (controlling for LTP and LTD) become impaired in old animals. But still there, but less active.
Author
ID
318162
Card Set
Mcb165 lec 17
Description
Neurodengeration
Updated
Show Answers