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Small molecule (catabolite) in lac repression?
Glucose
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Small molecule in Npr repression?
a-ketoglutyrate
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Small molecule inducer in lac
cAMP
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Che(x) protein functions
- MCP - Transmembrane kinase
- W-A - First component (phos)
- B - P, demethylates MCP
- Y - P, Binds to flagellar switch
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Attractants increase/decrease
Run(ccw)/tumble(cw)
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Quorum sensing (incl. molecule)
- Chemical detection of presence of same bacteria
- Acyl homoserine lactone
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Sporulation in bacillus
- Sigma factors used in crosstalk
- (F, E) - Endospore
- (G, K) - Mother cell
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Uses of quorum sensing
- Bioluminescence (aliivibrio fischeri)
- Toxin production (e. coli)
- Biofilm (pseudomonas aeruginosa)
- Sporulation (bacillus)
- Differention (caulobacter)
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Swarmer and stalked cells
- Quorum sensing - Differentiation
- Swarmer - Dispersal
- Stalked - Reproduction
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Types of regulatory RNA
- RBS blocking
- Antisense - From nontemplate DNA, multiple sites, can enhance translation
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