Parasitology Quiz 2

  1. Infective entities in Apicomplexans
  2. Develops within the oocyst and contains sporozoites
  3. Motile stage formed from asexual reproduction within the host cell
  4. Merozoite with slow growth & replication
  5. Merozoite with rapid growth & replication
  6. These circulate in the blood and are vector-born
  7. Hemoprotozoan life cycle
    • 1. Sporozoites excyst from sporocyst and invade cells
    • 2. Under asexual reproduction forming merozoites
    • 3. merozoites leave cells and invade new cells
    • 4. eventually form gametocytes
  8. Microgametocytes are
  9. macrogametocytes are
  10. Apicomplexan characteristics
    • obligatory intracellular
    • multiply through strict sequence of asexual & sexual reproduction
    • have direct or indirect life cycles
  11. Amblyomma americanum is definitive host
    Cytauxzoon felis
  12. Cytauxzoon felis transmission
    • Adult tick transmits sporozoite to intermediate host
    • Asexual reproduction in monocytes (1-2 rounds)
    • Monocytes rupture, releasing merozoites
    • Merozoites infect RBCs - ring stage
  13. Causes obstruction of vessels, splenic congestion, and pulmonary edema/congestion
    Cytauxzoon felis
  14. Sudden onset anemia, icterus, bile stasis
    Cytauxzoon felis
  15. Cytauxzoon felis is distributed in
    south-central US
  16. Seasonality of Cytauxzoon felis
    Peaks in spring- early summer, declines over summer, increases again in the fall
  17. Best tissue aspirates for Cytauxzoon felis
  18. Definitive host for Hepatozoon americanum
    Amblyomma maculatum
  19. Hepatozoon americanum direct or indirect life cycle?
  20. Intermediate host for Hepatozoon americanum
  21. Life cycle of Hepatozoon americanum
    • 1. Ticks ingest gamonts (gametocytes)
    • 2. Sexual reproduction forming oocysts
    • 3. Canid eats tick
    • 4. Sporozoites enter host's tissue
    • 5. Asexual reproduction to merozoites
    • 6. eventually enter leukocytes
  22. Paratenic host for Hepatozoon americanum
    small mammals
  23. What happens when small mammals eat a tick infected with Hepatozoon americanum?
    It enters cells and forms a cystozoite
  24. This causes periosteal proliferation of long bones
    Hepatozoon americanum
  25. Causes nonregenerative anemia with profound neutrophillic leukocytosis
    Hepatozoon americanum
  26. Lameness, muscle atrophy, painful
    mucopurulent ocular discharge
    Hepatozoon americanum
  27. Pathoneumonic onion skin lesion on muscle biopsy
    Hepatozoon americanum
  28. Definitive host(s) for Hepatozoon canis
    • Rhipcephalus sanguineus
    • Amblyomma sp
  29. Infects neutrophils and causes mild disease or might be clinically normal
    Hepatozoon canis
  30. Is a blood smear adequate for Hepatozoon americanum?
    Not unless the organism is circulating in the blood
  31. Is a blood smear adequate for Hepatozoon canis?
    Yes, it infects all of the neutrophils
  32. Definitive host for Babesia
    Ixodid ticks
  33. Life Cycle of Babesia spp
    • 1. Sporozoites transmitted through blood feeding
    • 2. Invade RBCs, undergo asexual reproduction
    • 3. Merozoite invades new blood cells
    • 4. Form gamonts which are ingested by tick
    • 5. Form zygote within tick which forms oocyst
    • 6. Sporozoites develop within oocyst
    • 7. Sporozoites go to salivary gland of tick
  34. Transmission of Babesia spp
    • Ticks
    • Direct animal to animal - dog fights
    • transplacental
    • transfer of blood
  35. Transmitted by Rhipcephalus sanguineus
    Babesia canis vogeli
  36. Babesia spp - Puppies are more severely affected than adults
    Babesia canis vogeli
  37. Babesia very common in greyhounds
    Babesia canis vogeli
  38. Babesia spp very common in fighting dogs
    Babesia gibsoni
  39. Causes sick dog syndrome
    Canine Babesiosis
  40. Clinical signs of Canine Babesiosis
    • hemolytic anemia, ischemic tissue injury
    • hypotensive shock syndrome
  41. Clinical findings for Canine Babesiosis
    • Thrombocytopenia (decreased platelets)
    • anemia
    • hyperglobinuria
  42. Detection method of choice for Canine Babesiosis
  43. Treatment outcomes for Canine Babesiosis
    • Complete cure
    • subclinical carrier
    • partial recovery (anemia remains)
    • relapse
  44. Bovine Babesiosis species of importance
    • B. bigemina
    • B. bovis
  45. Transmission of  bovine babesiosis
    • Rhipicephalus annulatus
    • Rhipicephalus microplus
  46. Is B. bovis or B. bigemina more pathogenic?
    B. bovis
  47. Babesia caballi & Babesia equi transmit
    Equine piroplasmosis
  48. Transmission with B. caballi
  49. Transmission with B. equi
  50. Ticks involved in Equine Piroplasmosis
    • Amblyomma cajennense
    • Dermacentor nitens
    • Dermacentor variabilis
    • R. microplus
  51. Transmission outside of Texas is
  52. Test of choice for Equine piroplasmosis
Card Set
Parasitology Quiz 2