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2 factors causing emergence of new epidemics
- prescribing too many antibiotics --> diseases mutate a lot, so we have to keep coming up with new medicines for it
- environmental changes --> flooding, changing weather patterns
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Who is John Snow? What was he known for?
- father of epidemiology
- british cholera epidemic - inspected water pumps to see what was causing the disease
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Outbreak Investigations (6 steps)
- 1. establish case definition - specific set of people that fit the disease
- 2. confirm suspected cases - asking questions related to case and try to figure out a reason for disease
- 3. define population denominator - limit it to people within a radius
- 4. review the literature - read about stuff relating to case
- 5. exposure assessment - make sure affected people were contaminated b/c of possible site and not other sites
- 6. generate plausible hypothesis
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Incidence vs. Prevalence
- incidence = number of new cases / total population
- prevalence = number of all cases / total population
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What does prevalence NOT include?
doesn't count all the people who already died
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Prospective Studies vs. Retrospective Studies
- prospective - begins at beginning and follows people over time
- retrospective - begins today, look backwards to see what happened to people in the past
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The two types of epi studies?
- descriptive studies --> describes the occurrence of the outcome, examining distribution of disease and observing basic features
- analytic studies --> describes association between exposure and outcome, tests hypothesis about cause by studying how exposure relates to disease
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3 types of descriptive studies?
- case report studies - unusual findings
- case series - multiple cases of findings
- description epidemiology studies - population based cases with denominator, look at entire population that are exposed
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2 types of analytic studies
- observational
- experimental
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3 types of observational analytic studies?
- case control studies --> determines and compares exposures, not outcomes
- cohort studies --> compares incidence of outcome to see if exposure leads to the outcome (all have been exposed but you observe which ones get affected)
- cross-sectional studies --> aka prevalence study, single period of observation (today), exposure and disease info is collected at the same time
- randomized control trial studies --> planned experiment with group of people, 2 groups (1 is the control), designed to test how effective the intervention/clinical treatment is, completely randomized
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Triad for descriptive studies
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Triad for analytic studies
- host - person that is affected
- agent - factor that is essential for transmittance of disease
- environment - factor that affects the agent
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Sensitivity
ability of a test to correctly identify those who have the disease
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Specificity
- the ability of a test to correctly identify those who do not have the disease
- SpPin
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High sensitivity = ?
few false negatives
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High specificity = ?
few false positives
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When is it better to have test of specificity vs. test of sensitivity?
- specificity - better to test if the treatment is harmful (chemo for cancer)
- sensitivity - better to have this test when you need to detect something early on (cancer)
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Problems with sensitivity and specificity? Sometimes so good that ___?
- specificity - sometimes so good at finding negatives that it gives false negatives
- sensitivity - sometimes so good at finding positives that it gives false positives
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Sensitivity formula
true positive / (true positive + false negative)
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Specificity formula
true negative / (true negative + false positive)
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False positive
test indicates disease but there is actually no disease present
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False negative
test indicated no disease there actually is a disease
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4 Key features of health statistics
- population based - usually a small sample of overall population
- measure wide range of health indicators for a community (entire country or state or county)
- collected/analyzed over a period of time (months, years, etc)
- include different types of data - vital, morbidity, mortality, use & cost of health care
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Assessing quality of health data (5 things)
- nature (source) of data
- availability of data
- validity and reliability of measures
- completeness of population coverage
- strengths & limitations of study design
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what do health statistics provide?
key indicators about life and health in a particular region
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Reliability vs. Validity of data
- reliability - consistent, meaning it is collected in the same way over multiple years
- validity - accuracy
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A reliable measure is usually free from ____
measurement error or bias
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Scale is valid if _______
if it measures what it intends to measure without systematic error
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Completeness of the data
representative of entire parent population
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Snowball sampling
network effect, one person can go out and recruit other similar people
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Generalizability (external validity)
ability to apply findings to a people that did not participate in a study
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Thoroughness
care it take to identify all cases of a given disease
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How to find health statistics? (4 steps)
- formulate the question
- choose the best resources for the question
- evaluate the results
- repeat as necessary
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What are the two types of diseases?
- Infectious (communicable)
- Chronic (non-communicable)
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What are infectious diseases?
- communicable diseases
- caused by pathogenic microorganisms (bacteria, viruses, parasites, fungi)
- can be spread directly or indirectly
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What are the 2 types of infectious diseases?
- emerging - newly identified, previously unknown infectious agents that cause public health problems either locally or internationally
- re-emerging - known for some time, fell to low levels, and now showing upward trends in incidence or prevalence worldwide
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What is a chronic disease?
- non-communicable
- not passed from person to person
- of long duration and generally slow progression
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4 main types of chronic diseases?
- cardiovascular --> diseases of blood vessels of the heart (stroke, heart disease)
- cancers --> severe health consequences, generally not very treatable
- chronic respiratory diseases
- diabetes --> increased blood sugar levels
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Causes and 2 types of diabetes? & a third type?
- due to a lack of insulting or an inability or body's tissues to respond properly to insulin
- type 1 --> need for lifelong insulin therapy
- type 2 --> related to insulin resistance, managed with diet and exercise
- gestational diabetes --> develops during pregnancy
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disease vs. illness
- disease - pathological changes within the body which are expressed in various physical signs and symptoms (symptoms during pregnancy)
- illness - an individual's subjective interpretation and response to these signs and symptoms (ancestor coming & possessing body)
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What is culture?
a system of thoughts and behaviors shared by a group of people
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cultural characteristics
- communication
- orientation to space & time
- social organization
- family structure
- gender roles
- religion
- social factors
- stigmatization of illness
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Contested illness
- where sufferers claim to have a specific disease that many physicians don't recognize or acknowledge as medical
- ex: chronic fatigue
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medicalization
- when human problems or experiences become defined as medical problems
- ex: madness, drug & alcohol problems, menopause, baldness
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What is a social construction?
- a conceptual frame work that emphasizes the cultural and historical aspects of phenomena widely thought to be exclusively natural
- AND
- examines how individuals and policy groups contribute to producing perceived social reality and knowledge
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Long term trends in socioeconomic status & health
- better sanitation, clean water, etc
- diseases of affluence (CHD, stroke, obesity)
- disease patterns are changing
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Inequity vs. inequality
- inequity - unfair or unjust
- inequality - unequal
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Fixed vs. fluid factors in health
- fixed --> things that cannot be changed, genetic or biological differences
- fluid --> things that can change and we don't have control over (age, income, where you live)
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What is social epidemiology?
studies the social distribution and social determinants of health based on things like socioeconomic states, gender & ethnicity
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Problem with social epidemiology?
doesn't take genetics or lifestyle into account
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Social ecological model
factors that influence a person's health/choices
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Income vs. consumption vs. wealth
- income --> the amount that can be spent/consumed within a given time
- consumption --> amount of resources actually used within a given time
- wealth --> total value of assets and liabilities at any point in time
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Intersectionality
the study of overlapping or intersecting social identities and related systems of oppression, domination or discrimination
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Observation about immigrants and their health over time?
first generation migrants are generally much healthier than their children (health gets worse over time) -- don't know why
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2 examples of disparities in health care?
- blacks have a higher rate of infant mortality than other racial groups
- blacks go to the emergency room more than regular doctor's office
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Gender vs sex
- gender --> socially constructed term referring to roles, behaviors, activities, and attributes that a given society considers appropriate for men & women
- sex --> defined biologically & physiologically
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sexual orientation
a person's emotional, sexual, and/or relational attraction to others
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MSM vs. WSW acronyms
- msm = men who have sex with men
- wsw = women who have sex with women
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gender identity
person's internal sense of being male, female, or something else
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heterosexism
denying any non-heterosexual behavior
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transphobia
fear/hatred of somebody because they are trans
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the higher your social integration, the _________
higher your social construct
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when is environmental justice achieved?
when everyone, regardless of race, culture, or income enjoys the same degree of protection from environmental and health hazards and equal access to the decision-making process to have a healthy environment in which to live, learn and work
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what are neglected tropical diseases?
a medically diverse group of tropical infections which are especially common in low-income populations in developing regions of Africa, Asia and the Americas
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3 types of disease prevention
- primary - reducing the risk and avoiding problems before they start
- secondary - taking action to stop risk behaviors before an actual illness
- tertiary - treatment / rehabilitation after an illness
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Stages of change model is also known as?
transtheoretical model
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Stages of Change Model (list 6 steps)
- pre contemplation --> no intention to adopt change within next 6 months, unaware of their issues
- contemplation --> acknowledges there is a problem, intends to make change within the next 6 months but not committed yet
- preparation --> planning on making behavior change within the next month, may doubt their abilities but collects info
- action --> now making changes to modify behaviors, this phase includes a lot of time, money and energy
- maintenance --> sustain changes for 6 months or more, try to prevent relapse and avoid temptations
- relapse --> going back to previous behavior, can happen at any stage throughout the cycle
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