Biochem 4000 - Lecture 5 PI

  1. Tertiary structure
    Spatial orientation of secondary structures and side chains (and domains in multidomain proteins)
  2. Four main domain types
    • α
    • β
    • α/β
    • α+β
  3. α domain
    • Mainly α-helices
    • Bundles and orthogonal helices
  4. β
    • Mainly β-strands
    • Barrels or open sheets
  5. α/β and α+β domain differences
    • α/β is mainly parallel
    • α+β is mainly antiparallel
  6. Lone helix
    • Single helix combining into a quaternary structure (arguably a true domain)
    • - Keratin, alamethicin
  7. αα-hairpin
    • Helix-turn-helix (antiparallel)
    •  - rop protein
  8. Topology
    Pattern of connections between secondary structures and their arrangement
Author
Ant
ID
316417
Card Set
Biochem 4000 - Lecture 5 PI
Description
Biochem 4000
Updated