Biochem - Unit II - Steroids

  1. Describe the structure of cortisol, aldosterone, testosterone, estradiol (ie. the hydroxylase enzymes needed for their synthesis
  2. Describe the control of cortisol production
  3. Explain molecular mechanism of steroid hormone action and its application to the treatment of breast cancer.
  4. Cortisol
    • 21 hydroxylase
    • 17 hydroxylase
    • 11 hydroxylase
  5. Aldosterone
    • 21 hydroxylase
    • 18 hydroxylase
    • 11 hydroxylase
  6. Estradiol
    17 hydroxylase
  7. Testosterone
    17 hydroxylase
  8. Transport of sex hormone
    • Sex hormone-binding globulin (SHBG)
    • binds and transports
    • testosterone and estradiol
  9. Transport of cortisol
    • Corticosteroid Binding Globulin (CBG)
    • binds and transports cortisol
  10. specificity of Steroids' action is due to
    the specific intracellular receptor
Author
akhan
ID
316298
Card Set
Biochem - Unit II - Steroids
Description
Biochem - Unit II - Steroids - SC
Updated