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Species
order second, lowercase, italicized or underlined
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Genus
order first, uppercase, italicized or underlined
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first to described live microorganisms
Anton von Leeuwenhoek
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Antibiotics
Alexander Fleming
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microorganisms are present in the air (no spontaneous generation)
Louis Pasteur
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discovered that living things are made of cells
Robert Hooke
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vaccination
Edward Jenner
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Proved that a specific microbe causes a specific diseases
Robert Koch
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study of bacteria
Bacteriology
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study of protozoa and parasitic worms
Paristology
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study of immunity
Immunology
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study of viruses
Virology
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study of an organism's genes
Genomics
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DNA made from two different sources
Recombinant DNA
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the study of how microbes inherit traits
Microbial Genetics
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the study of how DNA directs protein synthesis
Molecular Biology
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microbes normally present in and on the human body
Normal microbiota (or flora)
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ability of body to ward off diseases
Resistance
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Microbes attach to solid surfaces and grow into masses
Biofilms
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new disease and diseases increasing in incidence
Emerging infectious diseases (EIM)
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One circular chromosome, not in a membrane
No histones
No organelles
Bacteria: peptidoglycan cell walls
Archaea: pseudomurein cell walls
Binary fission
Prokaryote
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Paired chromosomes, in nuclear membrane Histones
Organelles
Polysaccharide cell walls
Mitotic spindle
Eukaryote
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Staphyl (Prokaryote Shape)
cluster of cells
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Coccus (Prokaryote Shape)
spherical shaped
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Strepto (Prokaryote Shape)
chain of cells
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Diplo (Prokaryote Shape)
paired cells
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Vibrio (Prokaryote Shape)
bent shaped
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Eukaryote Def.
larger and more complex type of cell with a nucleus and organelles
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Prokaryote Def.
smaller and simpler type of cells with no nucleus or organelles
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Spirillium (Prokaryote Shape)
spiral shaped
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Bacillus (Prokaryote Shape)
rod shaped
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ability of an organism to move by itself
Motility
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Rotate (clockwise, counterclockwise) to push the cell
Flagellum movement
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Move toward or away from stimul
Taxis
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In spirochetes Anchored at one end of a cell Rotation causes cell to move
Axial Filaments (aka “endoflagella”)
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Facilitate transfer of DNA from one cell to another, Twitching motility, Gliding motility
Pili
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The Cell Wall
- Major function: prevent osmotic lysis
- Antibiotics interfere with peptidoglycan synthesis
- Made of peptidoglycan (in bacteria) Polymer of disaccharide
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Cell Wall Def.
exterior protective layer made of peptidoglycan
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short extensions for attachment
Frimbae
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Extracellular polysaccharide layer that allows cell to attach
Glycocalyx
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Gram-positive Cell Wall
- Thick peptidoglycan
- Teichoic acids
- 2-ring basal body
- Disrupted by lysozyme
- Penicillin sensitive
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Gram-negative Cell Wall
- Thin peptidoglycan
- Outer membrane
- Periplasmic space
- 4-ring basal body
- Endotoxin
- Tetracycline sensitive
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Wall-less Gram-positive cell due to Lysozyme digesting disaccharide in peptidoglycan
Protoplast
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Partially destroyed Gram-negative cell wall due to Lysozyme digesting disaccharide in peptidoglycan
Spheroplast
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wall-less cells that swell into irregular shapes
L forms
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Passive movement of H20 across a selectively permeable membrane
Osmosis
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No net movement of water
Isotonic
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Water movies into the cell which causes to burst (osmotic lysis)
Hypotonic
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Water moves out of the cell which shrinks (plasmolysis)
Hypertonic
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Coloring the microbe with a dye that emphasizes certain structure
Staining
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A thin film of a solution of microbes on a slide
Smear
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the chromophore is a cation
Basic dye
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the chromophore is an anion
Acidic dye
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Staining the background instead of the cell
Negative staining
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Differential stain used to distinguish gram + and – infections
Gram stain
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Differential stain used to identify mycobacteria infections
Acid fast stain
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Thin layer of peptidoglycan with waxy mycolic acid (mycobacteria)
Acid fast cell wall
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Thick layer of peptidoglycan and no lipopolysaccharide
Gram postive cell wall
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Thin layer of peptidoglycan with outer lipopolysaccharide
Gram negative cell wall
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Semipermeable phospholipid bilayer surrounding the cytoplasm
Plasma Membrane
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Area of cell that contains the circular chromosome
Nucleoid
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Movement of solutes through membrane proteins from high to low
Facilitated diffusion
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Specialized membranes for photosynthesis
Thylakoids
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Movement of solutes directly across membrane from high to low
Simple diffusion
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Smaller prokaryote enzyme used to make proteins
70S Ribosome
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Movement of solutes through membrane proteins from low to high with energy
Active transport
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Dormant and resistant reproductive structure
Endospore
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Passive transport
Simple diffusion, facilitative diffusion, osmosis
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Substances inside the cell but outside the nucleus
Cytoplasm
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Fluid portion of cytoplasm
Cytosol
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Microfilaments, intermediate filaments, microtubules
Cytoskeleton
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Membrane formation and secretion
Golgi complex
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Digestive enzymes
Lysosome
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Brings food into cells and provides support
Vacuole
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Lipid production
Smooth ER
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Protein production
Rough ER
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Host that sexual reproduction happens in
Definitive host
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Kingdom for insects
Animalia
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Arthropods that carry disease
Vector
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Phylum for insects
Arthropoda
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Harbors the parasite for a short time period
Intermediate host
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Class of fleas (Xenopsylla), lice (Pedicules), and flies with 6 legs
Insecta
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Class of mites (Sarcoptes) and ticks (Ixodes) with 8 legs
Arachnida
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Male and female reproductive organs in the same animal
Dioecious
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Contain a complete digestive system with a mouth and anus
Roundworm
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Separate male and female individuals
Monoecious
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Phylum of helminthes that is round and includes pinworms (Enterobius), Ascaris, hookworms (Ancylostoma), threadworms (Trichinella), and whipworms (Trichuris)
Nematoda
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Phylum of helminthes that is flattened and includes tapeworms (Class Cestoda) and flukes (Class Trematoda)
Flatworms
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Phylum of helminthes that is round and segmented and includes the leech (Hirudinea)
Annelida
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Contain an incomplete digestive system with one opening
Platyhelminthes
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Vegetative (feeding) stage of the protozoan lifecycle
Trophozoite
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Sexually transmitted Parabasalid with tufted flagella
Trichonomas
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Mode of protozoan sexual reproduction that involves fusion
Conjugation
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Blood borne Euglenozoan parasite with a flagella that is transmitted by the tsetse fly
Trypanosoma
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Hardy, dormant, and resistant stage of the protozoan lifecycle
Cyst
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Diplomonad intestinal parasite with an axoneme and two nuclei that forms cysts
Giardia
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Superkingdom of protozoa that includes Diplomonads, Parabasalids, and Euglenozoa
Excavata
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Mode of protozoan asexual reproduction similar to cell division
Schizogony
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Small ameboid Plasmodium trophozoite stage produced by schizogony in liver cells that infects red blood cells
Merozoite
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Amoebozoan intestinal parasite that moves by pseudopodia with a cyst that contains four nuclei
Entamoeba
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Male and female sexual cells of Plasmodium that form in the human bloodstream and unite to make zygotes in mosquitos
Gametocyte
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Superkingdom of protozoa that includes Apicomplexans, Dinoflagellates, and Ciliates
Chromalveolata
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A motile sporelike stage of Plasmodium that is typically the infective agent introduced into a host
Sporozoite
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Ciliate intestinal parasite with cilia for movement that contains a distinctive macronucleus
Balantidum
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Apicomplexan intracellular parasite transmitted by mosquitos, causes malaria, and enters cells using an apical complex
Plasmodium
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Algae with a glassy cell wall that form several crystalline shapes
Diatoms
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Photoautrophic organisms that lack the roots and stems of plants
Algae
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Algae with a cell wall of cellulose plates and a groove for a flagellum that causes toxic red tide blooms
Dinoflagellates
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Unicellular, eukaryotic organisms that are typically ingestive or absorptive heterotrophs including several medically important parasites
Protozoa
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Unicellular fungi that are identified by biochemical tests
Yeast
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Vegetative stage made up of a filamentous mass of cells
Mycelium
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Haploid nucleus of a donor cells penetrates a recipient cell making a cell with more than one nucleus
Plasmogamy
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Fusion of the nuclei in a cell to form a diploid zygote
Karyogamy
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Long filaments of cells that make up the fungus body
Hyphae
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Fungi that only produce asexual spores
Anamorphs
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Fungi that produce sexual and asexual spores
Teleomorphs
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Kingdom of mostly multicellular eukaryotes that are chemoheterotrophs and acquire food by absorption
Fungi
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Reproductive cells of fungi that are usually dispersed through the
air
Spores
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Club fungi that produce mushrooms and make basidiospores for sexual reproduction in a basidium
- Basidiomycota
- Basidiomycotina
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Mold that forms conidiophores and asci to produce asexual conidia spores and sexual ascospores
Aspergillus
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Black bread mold that forms zygopsores and sporangia to produce sexual zygospores asexual sporangiospores
Rhizopus
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Unusual eukaryotes that lack mitochondria and survive as intracellular parasites
Microsporidia
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Small mushroom that forms basidia to produce sexual basidiospores
Coprinus
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Unicellular Ascomycete yeast that is an opportunistic parasite
Saccharomyces
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Saprophytic molds that make zygospores for sexual reproduction
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Sac fungi including some molds and yeast that make an ascus reproductive structure containing ascospores
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