Pharmacologic Principles

  1. Study or science of drugs
  2. Any chemical that affects the physiologic processes of a living organism
  3. Describes the drug's chemical composition and molecular structure
    Chemical name
  4. Used in most official drug compendiums (PDR) to list drugs
    Generic name
  5. Nonproprietary name
    Generic name
  6. Drug's registered trademark
    Indicates that its commercial use is restricted to the owner of the patent for the drug
    Trade name
  7. Proprietary name
    Trade name
  8. The study of how various dosage forms influence the way in which the drug affects the body
  9. The study of what the body does to the drug
  10. The study of what the drug does to the body
  11. Focuses on the clinical use of drugs to prevent and treat diseases
  12. Study of the economic factors influencing the cost of drug therapy
  13. The study of poisons, including toxic drug effects, and applicable treatments
  14. Natural vs. synthetic drug sources
  15. Dissolving of solid dosage forms and absorption
  16. Movement of a drug from its site of administration into the bloodstream for distribution to the tissues
  17. Term to express the extent of drug absorption
  18. Two medications have the same bioavailability and same concentration of active ingredient
  19. Term meaning any route of administration other than the GI tract
  20. Application of medication to various body surfaces
  21. Transport of a drug by the bloodstream to its site of action
  22. Unbound portion of a drug that is pharmacologically active
    "Free" drug
  23. Occurs when the presence of 1 drug decreases or increases the actions of another drug that is administered concurrently
    Drug-drug interaction
  24. The biochemical alteration of a drug into an inactive metabolite, a more soluble compound, or a more potent active metabolite
  25. The time required for 50% of a given drug to be removed from the body
  26. Physiologic state in which the amount of drug removed via elimination is equal to the amount of drug absorbed with each dose
    Steady State
  27. Consistent levels of drug in the body that correlate with maximum therapeutic benefits
    Steady State
  28. The time required for the drug to elicit a therapeutic response
    Onset of action
  29. Time required for a drug to reach its maximum therapeutic response
    Peak Effect
  30. Length of time that the drug concentration is sufficient to elicit a therapeutic response
    Duration of action
  31. Highest blood level
    Peak Level
  32. Lowest blood level
    Trough Level
  33. Peak level is too high
  34. Ratio of a drug's toxic level to the level that provides therapeutic benefits
    Therapeutic Index
  35. Amount of drug in a given volume of plasma
    Drug Concentration
  36. Patient specific factors such as allergies or concurrent diseases or other medical issues
    Patient's condition
  37. Decreasing response to repeated drug doses
  38. Physiologic or psychological need for a drug
  39. Any patient condition that makes the use of the given medication dangerous for the patient
  40. An alteration of a drug's action by either other drugs, foods, OTC meds, herbal therapies, etc.
    Drug interaction
  41. When 2 parenteral drugs or solutions are mixed together and the result is chemical deterioration of the drugs and/or formation of a precipitate
  42. And undesirable occurrence involving medication
    Adverse drug event
  43. Any reaction to a drug that is unexpected and undesirable and occurs at therapeutic dose range
    Adverse Drug Reaction
  44. Adverse drug reaction that is an extension of the drug's normal effects in the body
    Pharmacologic reactions
  45. Adverse drug reaction that involves the patient's immune system
  46. Adverse drug reaction that occurs unexpectedly in a particular patient-not an allergy or known pharmacologic property of a drug
    Idiosyncratic reaction
  47. Drug-related effect that causes structural defects in the fetus
  48. Drug-related effect that causes permanent changes in the genetic compositions
  49. Drug-related effect that causes cancer
Card Set
Pharmacologic Principles
Pharmacologic Principles