Chapter 17

  1. Describe components of the blood.
    • Blood
    • plasam
    • Erythrocytes
    • Leukocytes 
    • Platelets
    • . Buffy coat
    • Hematocrit
  2. After centrifuging, of the listed blood components, which contains the components of immune function?
    Buffy coat (white blood cells)
  3. What percentage of our blood is plasma?
    • 55%
    • Which of the formed elements is present in the greatest concentration?
  4. Explain the functions of the blood?
    • Transport
    • Regulation
    • Protection
    • • Delivering O2 and
    • nutrients to body cells
    • • Transporting metabolic
    • wastes to lungs and
    • kidneys for elimination
    • • Transporting hormones
    • from endocrine organs to
    • target organs
    • • Maintaining body
    • temperature by
    • absorbing and
    • distributing heat
    • • Maintaining normal
    • pH in body tissues.
    • • Maintaining adequate
    • fluid volume in
    • circulatory system
    • Preventing blood
    • loss
    • – Plasma proteins and
    • platelets initiate clot
    • formation
    • • Preventing infection
    • – Antibodies
    • – Complement
    • proteins
    • – WBC
  8. Which of the following is a protective function of blood
    preventing infection
  9. Describe the characteristics of erythrocytes
    • Biconcave shape
    • >97% hemoglobin
    • Major factor
    • contributing to blood
    • viscosity
  10. Which of the following is a characteristic of a mature erythrocyte?
    It has a biconcave disc shape
    • • RBCs dedicated to
    • respiratory gas
    • transport
    • • Hemoglobin binds
    • reversibly with
    • oxygen
    • • Normal values
    • – Males - 13–18g/
    • 100ml; Females - 12–
    • 16 g/100ml
  12. Which of the following is a function of erythrocytes?
    to transport oxygen and carbon dioxide
  13. What is the name of the protein found in erythrocytes that transports respiratory gases?
  14. What triggers erythropoietin (EPO) production to make new red blood cells?
    reduced availability of oxygen
  15. What part of the body does erythropoietin (EPO) target to increase erythropoiesis?
    bone marrow
  16. Each hemoglobin can transport
    ________ oxygen molecules.
  17. Oxygen binds to the _______ portion of hemoglobin.
    iron atom
  18. Describe the  of the different types of leukocytes?
    • neutrophil : Multilobed nucleus, pale red and blue
    • cytoplasmic granules.
    • EOSINOPHIL: Bilobed nucleus, red
    • cytoplasmic granules.
    • basophil:Bilobed nucleus, purplish-black cytoplasmic granules'.
    • Lymphocyte:Large spherical nucleus, thin rim of
    • pale blue cytoplasm.
    • MONOCYTE: Kidney-shaped nucleus, abundant pale blue cytoplasm.

    • NEUTROPHIL: the most numerous type of white blood cell.
    • eosinophil: has a role in killing parasitic worms
    • basophil:  bilobed nucleus and  dark-staining cytoplasmic granules. 
    • lymphocyte:small agranulocyte with a lifespan that ranges from a few hours to decades.
    • Monocyte:U or kidney shaped in the nucleus.
  20. Two categories of leukocytes
    • Granulocytes – Visible cytoplasmic granules,
    • lobed nuclei, phagocogytic
    • – Neutrophils, eosinophils, basophils
    • Agranulocytes – No visible cytoplasmic
    • granules, spherical or kidney-shaped nulcei
    • – Lymphocytes, monocytes
  21. An elevated neutrophil count would
    be indicative of ________.
    an acute bacterial infection
  22. Antihistamines counter the actions of which white blood cells?
    Defense against disease
    • neutrophil: phagocytize bacteria
    • eosinophil:kills parasitic worms
    • basophil: release histamine and heparin when activated
    • Lymphocyte: makes B & T cells
    • Monocyte:develop into macorphage tissues
  24. Which type of leukocyte is responsible for antibody production?
  25. Identify the leukocytes in the figure in order.Image Upload 1
    neutrophil, eosinophil, basophil, lymphocyte, monocyte
  26. Which granulated leukocyte is most likely to be active during a bacterial infection?
  27. Understand how new blood is formed and where
  28. how erythropoiesis is regulated
  29. Describe the three steps of hemostasis
    • Vascular spasm: Smooth muscle contracts,
    • causing vasoconstriction. 
    • Platelet plug formation:Injury to lining of vessel exposes collagen fibers; platelets adhere. 
    • Coagulation: Fibrin forms a mesh that traps red blood cells and platelets,
    • forming the clot.
  30. Which of the following shows the correct sequence of hemostasis from start to end?
    vascular spasm, platelet plug formation, coagulation
  31. A positive feed back of hemostatis which stage?
    Plateltet plug formation
  32. Clotting stage:
  33. The immediate response to blood vessel damage is a ________.
  34. Why don't platelets form plugs in undamaged  vessels?
  35. only contact of platelets with exposed collagen fibers and von Willebrand factor causes them to be sticky and form plugs.
    Describe the ABO blood typing system and
  36. AB is considered to be the universal recipient.
  37. A person who lacks agglutinogen A but has agglutinogen B would have blood type:
  38. how blood type is determined
    by antigen A or B
  39. An individual who is blood type AB negative can.
    receive any blood type in moderate amounts except that with the Rh antigen.
  40. A person with type AB blood has
    A and B antigens and neither anti-A nor anti-B antibodies.
  41. What determines a person's ABO blood type?
    the antigens found on the RBCs
  42. A person with A+ blood has _______.
  43. anti-B antibodies
    • the A antigen on the surface of the red blood cells.
    • Rh antigen on the surface of the red blood cells
    • all of the above
  44. would make antibodies to the A antigen but not the B antigen.
    person with type B blood
  45. would make antibodies to the B antigen but not the A antigen
    person with type A blood
  46. would have type A and B antigens
    person with type AB blood
  47. would make antibodies to the A and B antigens
    type O
  48. Type A blood cannot be given to people with type B blood.
  49. A person with type B blood could receive blood from a person with either type B or type O blood
  50. .A person with type O blood has _______.
    neither A nor B agglutinogens
  51. Universal doner:
    Type O
  52. Understand why it’s important that donor and recipients be ‘matches’
  53. A mismatch of blood types during a transfusion is dangerous because ________
    preformed antibodies in the recipient's blood will bind and clump (agglutinate) the donated cells
  54. vocab
  55. Agglutinogens: an antigen that stimulates the production of an agglutinin.
    Agranulocytes: lack granular cytoplasm and have round nuclei.
    Anemia: – Blood has abnormally low O2-carrying capacity 
    Buffy coat:contains leukocytes and platelets.
    Erythrocytes: intracellular protein that binds oxygen and transports it, most abdunant, 250 million volume
    Formed elements:blood cells and cell fragments, white blood cells:leukocytes, defense cell
    red blood cells:erythrocytes
    -most abundant cell type
    -specialized for transporting oxygen
    platelets: cell fragments: clotting
    Granulocytes:a white blood cell with secretory granules in its cytoplasm, e.g., an eosinophil or a basophil.
    Hematocrit:s the percentage of erythrocytes in a whole blood sample. 
    Hematopoiesis:is the process of creating new blood cells in the body. 
    Hemocytoblasts:the parent cell all formed elements arise from the same type of stem cell.
    Hemoglobin:protein found in erythrocytes that transports respiratory gases
    Hemostasis: stoppage of bleeding
     lymphocytes:leukocyte is responsible for antibody production.
    Plasma: 55% of whole blood, 90 water
    Platelets: membrane-closed cytoplasmicn fragments: megakrocyte.
    Universal donor: 0
    Universal reciepent: type AB
    A person with type B blood can only give blood to people of type AB and B blood.
    incompatible transfusion:Donate type B blood to a recipient with type O blood.
Card Set
Chapter 17
Blood study guide m and p