DNA Replication Components

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  1. Origin of Replication
    Replication of chromosomes begins here.
  2. Parent Strands
    DNA creates daughters by using the parent strand as a template/guide.
  3. Leading Strands
    DNA pol III remains in the replication fork on a template strand and continuously adds nucleotides to the new complementary strand as the fork progresses. The DNA strand made b this is the leading strand.
  4. Lagging Strand
    A primase "reads" the tempate DNA and initiates sythesis of a short complementary RNA primer. A DNA polymerase extends the primed segments, forming Okazaki fragments. The RNA primers are then removed and replaced with DNA, and the fragments of DNA are joined together by DNA ligase.
  5. RNA primer
    Begins DNA replication by providing beginning nucleotides.
  6. Replication Fork
    A Y-shaped region where the parental strands of DNA are being unwound.
  7. Primase
    Synthesizes the RNA primer using the parental DNA as template.
  8. Single-Strand Binding Proteins
    Stabilize the unwound parental strands.
  9. Helicase
    Unwinds and separates the parental DNA strand.
  10. Topoisomerase
    Breaks, swivels, and rejoins the parental DNA ahead of the replication fork, relieving the strain caused by unwinding.
  11. DNA Polymerase
    Catalyze the synthesis of new DNA by adding nucleotides to a preexisting chain.
  12. DNA Ligase
    Joins the sugar-phosphate backbones of all the Okazaki fragments into a continuous DNA strand.
Card Set
DNA Replication Components
CNU biology 211
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