Pharmacology Dr. Brown Ch 12 Antiparasitics

Ideal characteristics of antiparasitics

Dog breed sensitive to Ivermectins

Inhibitory neurotransmitter involved with the effects of diazepam tranquilizers

Tapeworm segments

Type of cholinergic receptors that when stimulated produce muscle tremors and eventually paralysis

Compounds that specifically inhibit coccidia protozoa

Means dilated pupils

Term used to describe compounds that kill flukes

Condition that occurs after recovery from acute organophosphate toxicosis

Cholinergic receptor that when stimulated produce SLUDDE signs of organophosphate toxicosis

Anthelmintics that kill both internal and external parasites

Neurotransmitter associated with parasympathetic effects

General term used to describe compounds that kill a wide range of internal parasites

Molecule responsible for moving drugs like ivermectin from the CNS into the blood; part of the blood-brain barrier functional mechanism

Term used to describe compounds that kill worms that are round in cross-section

Inhibitory neurotransmitter thought now to account for the effects of ivermectin

Refers to something that floats along in the blood vessel until it lodges and causes obstruction

Type of drug that kills heartworm adult worms

Term used to describe compounds that kill protozoa

Parasites that live on the outside of the animals body

Means coughing up blood

Means kills parasite egss

Enzyme that destroys acetylcholine to terminate its action

Means itching

Term used to describe compounds that kill tapeworms

Compounds that kill young produced by adult heartworms

Means that an insecticide is much more poisonous to the parasite than it is to the host animals

Advantage active ingredient

Program active ingredient

Immiticide active ingredient

Revolution active ingredient

Interceptor active ingredient

Heartgard active ingredient

Sentinel active ingredient

Panacur active ingredient

Strongid, Nemex active ingredient

Droncit active ingredient

Frontline, Top Spot active ingredient

Capstar active ingredient

One of the safest groups of external insecticides characterizied by its quick knock down made from chrysanthemum

Group of internal and external antiparasitic drugs that works primarily by stimulation of the inhibitory neurotransmitter glutamate receptors

Originally developed for demodicosis, toxic if ingested. a2 agonist.

Toxicosis from endectocide results in CNS depression and is exhibited by ataxia, depression, blindness, and coma

Safe roundworm medication found in grocery store, OTC, vermifuge.

Topically administered endectocide, controls fleas and ticks, ear mites, sarcoptic mange, avermectin-type drug

Antiprotozoal used in calves and avian species, causes thiamin deficiency

Arsenical adulticide against Dirofilaria, requires deep IM injection

Drugs blocked from getting to the brain by P-glycoprotein

Group of insecticides that works by blocking acetylcholinesterase

Milbemycin type of antiparasitic approved for cattle and horses, active ingredient in Proheart 6

Prototype drug for benzimidazoles

Antiprotozoal drug developed to be effective against agent that causes EPM

Microfilaricide most commonly used

Benzimidazole approved for use in dogs horses and livestock, trade name Safe-guard

Antinematodal pleasant tasting liquid suspension given PO

Toxic signs include SLUDDE or muscle tremors progressing to paralysis

Single-treatment tapeworm medication

HW preventative avermectin approved for use in cats and dogs once a month, first canine HW preventative

Oral macrolide HW preventative but not an avermectin

Topically applied flea insecticide, blocks nicotinic receptors

Flea tablet, inhibits chitin formation in larave and egg

Daily administered oral HW preventative medication

Macrolide HW preventative used in dogs and cats that is similar in structure as avermectins, treats ear mites in cats

Antibacterial drug that is also antiprotozoal, has neurological effects at high doses

Injectable and pour on avermectin type drug approved for use in cows and pigs

Insecticides associated with SLUDDE signs

Added to pyrethrins to increase their killing activity, synergist drug

Topically applied insecticide removes inhibitory effect of GABA on the nervous system

Antidote for organophosphate or carbamate toxicosis

Oral tablet flea adulticide, rapid death of fleas, nicotine type compound stimulates muscle movement and paralyzes the fleas

JHM for fleas, larvae dont mature to adults

Insect repellent often used in human repellent products, can cause neurologic side effects