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  1. Antihistamines
    • Hydroxyzine
    • * Administer IM, deep in large muscle. Do Not give IV or subq
    • *Monitor for sedative effects.
    • * Adverse effects include HA, hypotension, dry mouth, dizzinessand hives.
  2. Benzodiazepines
    • -zepam
    • Alprazolam
    • * Contraindicated in patients with narrow angle glaucoma.
    • * Adverse effects include drowsiness, dizziness, sedation,retrograde amnesia, hypotension, GI complaints and HA.
  3. Phenothiazines
    • -azine
    • * Multiple adverse effects, choose the agent with the least advers patient.
    • *Thorazine may produce pronounced orthostatic hypotension
    • * Adverse effects include: extrapyramidal reactions, neurolepticmalignant syndrome, seizures, anorexia, urinary retention, drymouth, leukopenia, agranulocytosis, sedation and tardivedyskinesia after prolonged use.
  4. Nonphenothizines
    • Haloperidol
    • *Contraindicated with narrow angle glaucoma, severe hepatic,renal, or cardiovascular disease, or Parkinson’s disease
    • *Serious or life-threatening adverse reactions include:tachycardia, seizures, urinary retention, respiratory depression,laryngospasm, neuromalignant syndrome, and dysrhythmias
  5. Atypical Antipsychotics
    • Risperidone, Quetiapine, Aripiprazole
    • * Less likely to cause extrapyramidal effects, neurolepticmalignant syndrome and tardive dyskinesia than thephenothizines.
    • * Adverse effects include sedation, drowsiness, appetitestimulation with weight gain, orthostatic hypotension, HA, drymouth, agitation and anxiety.
  6. (SSRIs)
    • Fluoxetine, Paroxetine, Escitalopram, Citalopram, Sertraline HCl
    • * Adverse effects include insomnia, weight gain, sexualdysfunction, palpitations, HA, seizures, diaphoresis, and GIcomplaints.
    • * Do not give with MAO inhibitors. Wait 14 days after stopping MAOIs to administer
  7. (MAOIs)
    • Phenelzine, Tranylcypromine
    • * Adverse effects include: dizziness, orthostatic hypotension,constipation, diarrhea, tremors, seizures, coma, tachycardia,diaphoresis, sexual dysfunction, weight gain.
    • * Teach to avoid tyramine containing foods and beverages(pickled, aged, fermented or caffeinated). Hypertensive crisiscan be triggered by foods rich in tyramine.
    • * Contraindicated with concurrent use of meperidine,barbiturates, tricyclic antidepressants, antihistamines, CNSdepressants, and OTC cold medicines.
    • * Teach client to not take any other medications withoutchecking with healthcare provider when taking an MAOIs
  8. Tricyclic Antidepressants
    • Amitryptyline, Nortriptyline, Imipramine
    • * Adverse effects include: Orthostatic hypotension, HA, drymouth, sedation, urinary retention, dysrhythmias andimpotence.
    • * Overdose is generally lethal.
    • * Cautious use in patients with suicidal ideations.* Contraindicated with history of seizures or chronic cardiacdisease.
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