-
hydrocodone bitartrate with acetaminophen
- Brand Name: Lortab
- Therapeutic Class: analgesic combination (opioid)
- MOA: hydrocodone: opioid receptor agonist, acetaminophen: analgesic MOA unknown
-
levothyroxine
- Brand Name: Synthroid
- Therapeutic Class: thyroid product
-
lisinopril
- Brand Names: Prinivil, Zestril
- Therapeutic Class: angiotensin-converting enzyme (ACE) inhibitor
- MOA: ACE-I (angiotensin converting enzyme inhibitor)
-
alprazolam
- Brand Name: Xanax
- Therapeutic Class: benzodiazepine
- MOA: binds to receptors in the central nervous system (CNS)
-
metformin
- Brand Name: Glucophage
- Therapeutic Class: antidiabetic agent
- MOA: main effect believed to inhibition of hepatic gluconeogenesis
-
furosemide
- Brand Name: Lasix
- Therapeutic Class: diuretic (loop)
- MOA: "loop diuretic": blocks sodium and chloride re-absorption from kidney tubules
-
omeprazole
- Brand Name: Prilosec
- Therapeutic Class: proton pump inhibitor
- MOA: PPI
-
simvastatin
- Brand Name: Zocor
- Therapeutic Class: antilipemic agent
- MOA: inhibits HMG Coenzyme A and upregulates hepatic LDL receptors
-
atorvastatin
- Brand Name: Lipitor
- Therapeutic Class: antilipemic agent
- MOA: inhibits HMG Coenzyme A and upregulates hepatic LDL receptors
-
amlodipine besylate
- Brand Name: Norvasc
- Therapeutic Class: calcium channel blocker
- MOA: dihydropyridine calcium channel blocker
-
albuterol sulfate (salbutamol)
- Brand Names: Proventil HFA, Proair HFA, Ventolin HFA
- Therapeutic Class: beta2 agonist
- MOA: beta-2 receptor agonist
-
zolpidem
- Brand Name: Ambien
- Therapeutic Class: hypnotic
- MOA: agonist of benzodiazepine GABA-A subunit
-
citalopram
- Brand Name: Celexa
- Therapeutic Class: antidepressant
- MOA: SSRI
-
hydrochlorothiazide
- Brand Name: Microzide
- Therapeutic Class: diuretic
- MOA: diuretic effect: blocks re-absorption of sodium and chloride from renal tubules, antihypertensive effect: unknown
-
gabapentin
- Brand Name: Neurontin
- Therapeutic Class: anticonvulsant
- MOA: unknown
-
ranitidine
- Brand Name: Zantac
- Therapeutic Class: histamine H2 antagonist
- MOA: histamine-2 (H2) antagonist
-
tramadol
- Brand Name: Ultram
- Therapeutic Class: analgesic (opioid)
- MOA: binds to opioid receptor and also inhibits reuptake of norepinephrine (NE) and 5-HT
-
aspirin, enteric-coated
- Brand Name: Bayer, St. Joseph
- Therapeutic Class: antiplatlet agent
- MOA: irreversible inhibitor of cyclo-oxygenase enzymes 1and 2
-
potassium chloride (oral)
- Brand Name: K Dur
- Therapeutic Class: electrolyte supplement
- MOA: potassium supplement
-
clonazepam
- Brand Name: Klonopin
- Therapeutic Class: benzodiazepine
- MOA: believed to enhance GABA activity
-
warfarin
- Brand Name: Coumadin
- Therapeutic Class: anticoagulant
- MOA: vitamin K epoxide reductase inhibitor (inhibitor factos II, VII, IX, and X)
-
montelukast
- Brand Name: Singulair
- Therapeutic Class: leukotiene receptor antagonist
- MOA: leukotriene receptor antagonist
-
metoprolol tartrate
- Brand Name: Lopressor
- Therapeutic Class: beta blocker
- MOA: beta-1 receptor blocker
-
cyclobenzaprine
- Brand Name: Flexeril
- Therapeutic Class: skeletal muscle relaxant
- MOA: reduces motor activity in brain stem
-
quetiapine
- Brand Name: Seroquel
- Therapeutic Class: antipsychotic agent
- MOA: serotonin (5HT), dopamie (DA), histamine and alpha receptor blockers
-
clopidogrel
- Brand Name: Plavix
- Therapeutic Class: antiplatelet agent
- MOA: platelet adenosine diphosphate (ADP) receptor antagonist
-
oxycodone
- Brand Name: OxyContin
- Therapeutic Class: analgesic opioid
- MOA: opioid receptor agonist
-
trazodone
- Brand Name: Desyrel
- Therapeutic Class: antidepressant
- MOA: unknown, believed to increase serotonin levels
-
carvedilol
- Brand Name: Coreg, Coreg CR
- Therapeutic Class: beta blocker with alpha-blocking activity
- MOA: non-selective beta receptor blocker
-
lovastatin
- Brand Name: Mevacor
- Therapeutic Class: antilipemic agent
- MOA: inhibits HMG Coenzyme A and upregulates hepatic LDL receptors
-
sertraline
- Brand Name: Zoloft
- Therapeutic Class: antidepressant
- MOA: SSRI (selective serotonin reuptake inhibitor)
-
duloxetine
- Brand Name: Cymbalta
- Therapeutic Class: antidepressant
- MOA: SSNRI (selective serotonin and norepinephrine reuptake inhibitor)
-
oxycodone with acetaminophen
- Brand Name: Percocet
- Therapeutic Class: analgesic (opioid)
- MOA: oxycodone: opioid receptor agonist, acetaminophen: analgesic MOA unknown
-
fluticasone with salmeterol
- Brand Name: Advair
- Therapeutic Class: beta2 agnoist
- MOA: fluticasone: inhibits phospholipase, prostaglandins, and leukotrienes (mediators of inflammation), salmeterol: beta-2 receptor agonist
-
insulin glargine (rdna origin)
- Brand Name: Lantus
- Therapeutic class: insulin (long-acting)
- MOA: synthetic insulin
-
metoprolol succinate
- Brand Name: Toprol-XL
- Therapeutic Class: 24:24 beta adrenergic blocking agent
- MOA: beta-1 receptor blocker
-
azithromycin
- Brand Names: Zithromax, Zmax
- Therapeutic Class: antibiotic
- MOA: inhibits microbial protein synthesis
-
fluoxetine
- Brand Name: Prozac
- Therapeutic Class: antidepressant
- MOA: SSRI
-
venlafaxine
- Brand Name: Effexor (XR)
- Therapeutic Class: antidepressant
- MOA: potentiate activity of serotonin, norepinephrine, and dopamine
-
atenolol
- Brand Name: Tenormin
- Therapeutic Class: antianginal
- MOA: beta-1 receptor blocker
-
amitriptyline
- Brand Name: Elavil
- Therapeutic Class: antidepressant
- MOA: increases 5HT and NE levels (prevents reuptake)
-
iprotropium with albuterol
- Brand Name: Combivent
- Therapeutic Class: anticholinergic agent
- MOA: ipratropium: anticholinergic (blocks activity at muscarinic smooth muscle receptor) albuterol: beta-2 receptor agonist (results in bronchial smooth muscle relaxation)
-
bupropion
- Brand Name: Wellbutrin (SR, XL)
- Therapeutic Class: antidepressant
- MOA: inhibits dopamine (DA) and norepinephrine (NE) uptake
-
esomeprazole
- Brand Name: Nexium
- Therapeutic Class: proton pump inhibitor
- MOA: PPI
-
lorazepam
- Brand Name: Ativan
- Therapeutic Class: benzodiazepine
- MOA: binds to receptors in the central nervous system (CNS)
-
fenofibrate
- Brand Name: TriCor
- Therapeutic Class: antilipemic agent
- MOA: peroxisome proliferator-activated receptor (PPAR) alpha agonist
-
escitalopram
- Brand Name: Lexapro
- Therapeutic Class: antidepressant
- MOA: SSRI
-
fluticasone (nasal)
- Brand Name: Flonase
- Therapeutic Class: corticosteroid
- MOA: glucocorticoid receptor agonist
-
prednisone
- Brand Name: Prednisone
- Therapeutic Class: corticosteroid
- MOA: inhibits phospholipase, prostaglandins, and leukotrienes (mediators of inflammation)
-
divalproex
- Brand Name: Depakote (ER)
- Therapeutic Class: anticonvulsant
- MOA: unknown...may increase brain GABA levels
-
clonidine
- Brand Name: Catapres
- Therapeutic Class: alpha2-adrenergic agonist
- MOA: alpha-2 receptor agonist
-
diltiazem
- Brand Name: Cardizem (CD)
- Therapeutic Class: antiarrhythmic agent
- MOA: non-DHP CCB
-
carisoprodol
- Brand Name: Soma
- Therapeutic Class: skeletal muscle relaxant
- MOA: unknown, works centrally to produce muscle relaxation
-
risperidone
- Brand Name: Risperdal
- Therapeutic Class: antimanic agent
- MOA: unknown, affects serotonin (5HT) and dopamine (DA) receptors
-
meloxicam
- Brand Name: Mobic
- Therapeutic Class: nonsteroidal anti-inflammatory drug (NSAID)
- MOA: ?
-
tolterodine
- Brand Name: Detrol (LA)
- Therapeutic Class: anticholinergic agent
- MOA: muscarinic receptor antagonist
-
topiramate
- Brand Name: Topamax
- Therapeutic Class: anticonvulsant
- MOA: unknown, believed to potentiate effects of GABA
-
ibuprofen
- Brand Name: Motrin
- Therapeutic Class: nonsteroidal anti-inflammatory drug (NSAID)
- MOA: ?
-
amoxicillin
- Brand Name: Amoxil
- Therapeutic Class: antibiotic
- MOA: inhibits cell wall synthesis of mucopeptide
-
naproxen
- Brand Name: Naprosyn
- Therapeutic Class: nonsteroidal anti-inflammatory drug (NSAID)
- MOA: ?
-
lisinopril and hydrochlorothiazide
- Brand name: Zestoretic and Prinizide
- Therapeutic Class: angiotensin converting enzyme (ACE) inhibitor
- MOA: ACE-I
-
metoclopramide
- Brand name: Reglan
- Therapeutic Class: antiemetic
- MOA: antiemetic: inhibits DA (dopamine) receptor, which increase vomiting threshold, GI motility stimulant: cholinergic activity becomes greater than that of dopamine, which increase smooth muscle response to ACg (acetylcholine) and causes GI motility
-
sulfamethazole with trimethoprim
- Brand name: Bactrim
- Therapeutic class: antibiotic
- MOA: sulfamethazole: inhibits production of dihydrofolic acid, which kills bacteria, trimethoprim: interferes with the production of folic acid. Again, bacteriocida
-
pioglitazone
- Brand name: Actos
- Therapeutic Class: antidiabetic agent
- MOA: peroxisome proliferator-activated receptor (PPAR) gamma agonist
-
aripiprazole
- Brand name: Abilify
- Therapeutic Class: antipsychotic agent
- MOA: partial DA and 5HT receptor agonist
-
alendronate
- Brand name: Fosamax
- Therapeutic Class: biphosphonate derivative
- MOA: osteoclast inhibitor
-
tiotropium
- Brand name: Spiriva
- Therapeutic Class: anticholinergic agent
- MOA: causes airway smooth muscle relaxation
-
tamsulosin
- Brand name: Flomax
- Therapeutic Class: alpha blocker
- MOA: alpha-1 receptor antagonist
-
pregabalin
- Brand name: Lyrica
- Therapeutic Class: analgesic
- MOA: unknown, may bind to alpha(2)-delta receptors in the CNS
-
glyburide
- Brand names: Micronase and DiaBeta
- Therapeutic Class: antidiabetic agent
- MOA: sulfonylurea. increases pancreatic insulin release
-
donepezil
- Brand name: Aricept
- Therapeutic class: acetylcholinesterase
- MOA: acetylcholinesterase inhibitor (AChE-I)
-
rosuvastatin
- Brand name: Crestor
- Therapeutic Class: antilipemic agent
- MOA: inhibits HMG Coenzyme A and upregulates hepatic LDL receptors
-
propoxyphen with acetaminophen
- Brand name: Darvocet
- Therapeutic Class: analgesic combination (opioid)
- MOA: acetaminophen: analgesic effect unknown, propoxyphene: binds to opioid receptor (like codeine, hydrocodone)
-
diazepam
- Brand name: Valium
- Therapeutic Class: benzodiazepine
- MOA: binds to receptors in the central nervous system (CNS)
-
spironolactone
- Brand name: Aldactone
- Therapeutic class: diuretic (potassium-sparing)
- MOA: aldosterone antagonist at the distal convoluted renal tubule
-
pantoprazole
- Brand name: Protonix
- Therapeutic Class: proton pump inhibitor
- MOA: PPI
-
lamotrigine
- Brand names: Lamictal and Lamictal XR
- Therapeutic Class: anticonvulsant
- MOA: unknown, may block neuronal sodium channels
-
levalbuterol
- Brand name: Xopenex
- Therapeutic Class: beta 2 agonist
- MOA: beta-2 receptor agonist (results in bronchial smooth muscle relaxation)
-
glipizide
- Brand name: Glucotrol
- Therapeutic Class: antidiabetic agent
- MOA: sulfonylurea, increase pancreatic insulin secretion
-
fexofenadine
- Brand name: Allegra
- Therapeutic Class: histimine H1 antagonist
- MOA: allergy related ?
-
pravastatin
- Brand Name: Pravachol
- Therapeutic Class: antilipemic agent
- MOA: inhibits HMG Coenzyme A and upregulates hepatic LDL receptors
-
estrogens (conjugated)
- Brand Name: Premarin
- Therapeutic Class: estrogen derivative
- MOA; estrogen receptor agonist
-
isosorbide mononitrate
- Brand Name: Imdur
- Therapeutic Class: vasodilator
- MOA: organic nitrate, which causes arterial and venous dilation
-
ciprofloxacin
- Brand Name: Cipro (XR)
- Therapeutic Class: antibiotic
- MOA: inhibits bacterial DNA synthesis
-
triamterene with hydrocholorthiazide
- Brand Name: Dyazide
- Therapeutic Class: diuretic (potassium sparring)
- MOA: triamterene: inhibits the re-absorption of sodium in exchange for potassium and hydrogen ions in the renal tubule, HCTZ: inhibits sodium and chlorine re-asborption at the distal renal tubule
-
promethazine
- Brand Name: Phenergan
- Therapeutic Class: antiemetic
- MOA: H-1 receptor blocker
-
allopurinol
- Brand Name: Zyloprim
- Therapeutic Class: xanthine oxidase inhibitor
- MOA: decreases uric acid production
-
nitroglycerin (sublingual and injectable)
- Brand Name: Nitrostat
- Therapeutic Class: vasodilator
- MOA: increases release of nitric oxide, resulting in vasodilation/relaxation of vascular smooth muscle
-
lansoprazole
- Brand Name: Prevacid
- Therapeutic Class: proton pump inhibitor
- MOA: PPI
-
paraoxetine
- Brand Name: Paxil
- Therapeutic Class: antidepressant
- MOA: SSRI
-
doxycycline
- Brand Name: Vibramycin
- Therapeutic Class: antibiotic
- MOA: inhibits bacterial protein synthesis
-
amphetamine and dextroamphetamine salts
- Brand Name: Adderall
- Therapeutic Class: stimulant
- MOA: sympathetic amine with effects similar to epinephrine
-
insulin aspart (rdna origin)
- Brand Name: Novolog
- Therapeutic Class: insulin, rapid acting
- MOA: synthetic insulin supplement
-
memantine
- Brand Name: Namenda
- Therapeutic Class: N-methyl-D-aspartate receptor antagonist
- MOA: NMDA receptor antagonist (n-methyl-D-aspartate)
-
fentanyl, transdermal
- Brand Name: Duragesic
- Therapeutic Class: analgesic (opioid)
- MOA: opioid receptor agonist
-
mirtazapine
- Brand Name: Remeron
- Therapeutic Class: antidepressant
- MOA: increases central NE and 5HT (serotonin) activity
-
ezetimibe
- Brand Name: Zetia
- Therapeutic Class: antilipemic agent
- MOA: cholesterol absorption inhibitor (CAI)
-
celecoxib
- Brand Name: Celebrex
- Therapeutic Class: nonsteroidal anti-inflammatory drug (NSAID)
- MOA: cyclo-oxygenase 2 inhbitor
-
hydroxyzine
- Brand Name: Atarax
- Therapeutic Class: antiemetic
- MOA: H1 receptor blocker
-
valsartan
- Brand Name: Diovan
- Therapeutic Class: angiotensin II receptor blocker
- MOA: angiotensin receptor blocker (ARB)
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