-
warfarin
- coumadin, jantoven
- anticoagulatn used to treat and prevent blood clots- inhibits vitamin K dependent clotting factors
- 2-5mg or 1-10 based on INR
- DI: many esp NSAIDs
- SE: many- hemorrage
-
Clopidogrel
- Plavix
- used after MI to prevent blood clot- prevents platelete aggregation by preventing ADP from binding to platelets
- 75mg daily
- DI: diltiazem, amlodipine, NDAID, SSRI, PPI
- SE: HA, abdominal pain, pupura, arthroalgia
-
Digoxen
- Lanoxin
- Cardiac arrhythmia
- inhibits NA K ATPase, an enzyme used to treat cellular action potential --> rhythm of cardiac muscle
- 0.125-0.25mg daily
- DI: Many- NSAID, macrolides, HCTZ
- SE: HA, NVD, dysthmias
-
Isoprbide Monotrait
- Imdur
- Nitrate: for angina
- relazes sm muscle in periphery --> vasodilation
- 30-120 daily
- DI: sildenafil, vardenafil, Talafil
- SE: HA, dizziness, orthostatic hypotension, NVD
-
Nitroglycerin
- Nitrobid, nitroquick
- nitrate- angina
- relazes sm muscle in periphery --> vasodilaion
- trans: 0.2-0.8mg.hr 12 on and 12 off
- subling: 0.4mg -- repeat q 5 min for 3 doses then call 911
- DI: sildenafil, vardenafil, taladfil
- SE: HA, dizziness, lightheadedness
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