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cell biology nbeo.txt
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What is the order of DNA replication?
Transcription = DNA to mRNA
Translation = mRNA to protein
What class of drugs attack 30s ribosomes?
Aminoglycosides
Tetracyclines
What class of drugs attack 50s ribosomes?
Macrolides
Where are steroids produced?
Adrenal cortex
What part of the cell is affected in tay sach's disease?
Lysosomes
What part of the cell is affected in leber's hereditary optic neuropathy and kearns-sayre syndrome?
Mitochondria
What is the main ion inside the cell?
K+
What is the ratio of Na/K pumped out of the cell?
3Na:2K
What is the main ion outside the cell?
Na+
What is depolarization?
Inside of cell becomes more positive = action potential
What is hyperpolarization?
Inside of cell becomes more negative = stalled action
What are the concentrations of intracellular, extracellular compartments and plasma in the body?
25L, 12L, 3L
What do A1 receptors do?
A+ MUScles are drinking their calcium
Increase intracellular calcium (together with muscarinic)
What are the locations of A1 receptors?
Radial iris dilator
Vascular SM
GI sphincters
What do A2 receptors do?
Decrease cAMP
Inhibitory response in heart, elsewhere = sympathetic
what do B1 receptors do?
Stimulate adenylyl cyclase
Increase cAMP
Where are the locations of B1 receptors?
Heart
Salivary glands
Adipose tissue
Kidneys
NPCE
What do B2 receptors do?
Increase cAMP
What are the locations of B2 receptors?
Bronchioles
GI tract
Bladder wall
Vascular SM
TM
CB
What is the only receptor to act on Na/K channels?
Nicotinic
A NaK for being unique
What are zonula occludens?
Impermeable Tight belt junctions around entire cell
BAB & BBB
What are zonula adherens?
Junctions that allow for intercellular passage
What are macula occludens?
Impermeable spot welds
What are gap junctions?
Channels connected to other channels for rapid electrical transfer = HDMI port
What type of cells are binuclear?
Hepatocytes
Cardiac muscle
Urinary tract epithelial cells
What type of cells are multinuclear?
Osteoclasts
Skeletal muscle
What type of cells are anuclear?
RBCs
What is contained within the nucleolus?
Dense chromatin
What does the nucleolus do?
Responsible for production of rRNA
What is rRNA?
Found in ribosomes
Responsible for protein translation
What is tRNA?
Responsible for translation
Which is transfer of amino acids to a growing protein
What do hepatocytes do?
Storage and breakdown of glycogen
Detox of lipid soluble drugs
What do ribosomes do?
Manufacture protein
What does smooth er do?
Lipid and steroid production
Produces fatty acids
What is rough ER responsible for?
Protein synthesis
What does the golgi apparatus do?
Modify and package proteins from rough ER to outside of cell
(fedex)
What do lysosomes do?
Trashmen
What does the mitochondria do?
Produces ATP
What do microtubules do?
Intercellular motility
What do intermediate filaments do?
Act as a super highway to/from nucleus
Gives resistance against external pressure on cell
What is the intracellular charge at equilibrium?
-90mV
Author
cjensen20
ID
303343
Card Set
cell biology nbeo.txt
Description
cell biology optometry NBEO
Updated
2015-05-29T03:15:51Z
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