SGU SVM Immunology

Body defenses that protect againts disease

• 1) Physical Barriers
• 2) Innate Immunity
• 3) Acquired Immunity
• 4) Passive Immunity

Chemicals and Cells

No Memory

Responds Immediately

Can recognize foreign invaders with specificity, destroy them, and retain the memory of the specific encounter.

Humoral Immunity and Cell-Mediated Immunity

Targets invaders outside of cells via B-lymphocytes

Targets cells of the body that are infected with Intracellular pathogens via T-lymphocytes

• 1) Hypersensitivities
• 2) Autoimmunity
• 3) Immunodeficiencies
• 4) Neoplasia of Immune System

Monocyte/Macrophages

Polymorphonuclear Cells

Don't recognize the antigen, they recognize infected cells by other mechanisms

• 1) Enzymes
• 2) Defensins
• 3) Interferons

Cause damage to membranes

Anti-bacterial peptides

Cytokines that can interfere with viral replication

Proteins that mediate cellular interactions and regulate cell growth and secretion.

Group of serum and cell surface proteins that can be activated by both innate and acquired immune mechanisms and result in a variety of biological events.

• 1) Cell Lysis
• 2) Chemotaxis
• 3) Opsonins