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Hem Lec 23

  1. Normal hemostasis depends on all of the following except?
    inadequate numbers of platelets
  2. The sequence of events following injury to a small blood vessel is?
    • Blood vessel spasm (vasoconstriction)
    • Formation of a platelet plug
    • Contact between damaged blood vessel, blood platelets,and coagulation proteins
    • Development of a blood clot around the injury
    • Fibrinolysis and reestablishment of vascular integrity
  3. Which blood vessels have the thickest walls?
    Arteries
  4. All blood and lymphatic vessels are lined with?
    endothelium
  5. Blood passes from the arterial to the venous system via
    capillaries
  6. The initiating stimulus to blood coagulation following injury to a blood vessel is?
    contact activation with collagen
  7. Which of the following is not correct?
    A. Vasoconstriction reduces blood fl ow and promotescontact activation of platelets and coagulation factors
    B. Platelets adhere to exposed endothelial connectivetissues
    C. Aggregation of platelets releases thromboxane A2and vasoactive amines (serotonin and epinephrine)
    None of the above
  8. Which of the following is not a characteristic of platelets?
    The presence of a nucleus
  9. The cellular ultrastructural component(s) unique to the platelet is (are)
    Glycocalyx
  10. At all times, approximately _____ of the total number of platelets are in the systemic circulation.
    two thirds
  11. The reference range of platelets in the systemic circulation is?
    150 to 450 × 109/L
  12. The functions of platelets in response to vascular damage include?
    formation of a platelet plug
  13. If vascular injury exposes the endothelial surface and underlying collagen, platelets 1._____ to the collagen fibers and 2._____.
    • 1. adhere
    • 2. aggregate
  14. Agents that are capable of aggregating platelets include?
    • collagen
    • thrombin
    • serotonin
  15. Aspirin ingestion has the following hemostatic effect in a normal person?
    Prolongs the bleeding time
  16. The bleeding time test measures?
    platelet adhesion and aggregation on locally injured vascular subendothelium
  17. The clot retraction test is?
    a refl ection of the quantity and quality of platelets and other factors
  18. Warfarin acts by?
    acting as a vitamin K antagonist
  19. Match the name of the coagulation factor with the appropriate symbolic designation:

    Thrombin
    IIa
  20. Match the name of the coagulation factor with the appropriate symbolic designation:

    Tissue thromboplastin
    III
  21. Match the name of the coagulationfactor with the appropriate symbolic designation:

    Antihemophilic factor
    VIII
  22. Match the name of the coagulationfactor with the appropriate symbolic designation:

    Hageman factor
    XII
  23. name step sin Platelet Plug Consolidation and Stabilization.
    Vascular injury → exposes subendothelium and vasoconstriction→ platelet adhesion → platelet aggregation →platelet plug formation → consolidation of platelets →fibrin stabilization
Author
CTEPBA
ID
302088
Card Set
Hem Lec 23
Description
Hem Lec 23
Updated

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