Hem Lec 19

  1. Replacement of normal marrow elements by leukocytic blasts and bleeding episodes.
    Blasts and immature leukocyte forms in the peripheralblood and anemia
    Leukocytosis
    typical characteristics of an acute leukemia
  2. FAB classification of Myeloid and monocytic leukemia?
    M4
  3. FAB classification of monocytic leukemia?
    M5
  4. FAB classification of Myeloid without maturation leukemia ?
    M1
  5. FAB classification of Lymphoblastic (one cell population) leukemia?
    L1
  6. Characteristics of FAB M1 include
    leukocytosis without maturation of the myeloid cellline in the peripheral blood
  7. The incidence of FAB M1 is
    • high in children younger than 18 months of age
    • high in middle-aged adults
  8. A mixture of myeloid and monocytic blasts  in peripheral blood is observed in which FAB classifications.?
    M4
  9. Blasts of the monocytic type in peripheral blood is observed in which FAB classifications.?
    M5
  10. Many coarsely granular promyelocytes with dumbbell-shaped or bilobed nuclei  in peripheral blood is observed in which FAB classifications.?
    M3
  11. Myeloblasts, promyelocytes, and myelocytes  in peripheral blood is observed in which FAB classifications.?
    M2
  12. Immature leukocytic and erythrocytic cell types  in peripheral blood is observed in which FAB classifications.?
    M6
  13. A common characteristic of ALL is
    bone and joint pain
  14. Myeloperoxidase differentiates?
    acute myelomonocytic from acute monocyticleukemia
  15. The PAS reaction is
    positive in the neutrophilic granulocytes, exceptblasts
  16. Specific nature B-cell surface marker(s) membrane is?
    • CD 79a
    • CD19C
    • CD 20
  17. Patients with AML have a good prognosis if?
    • Less than 45 years of age
    • Over rods are present in blast cells
    • Ph chromosome
Author
CTEPBA
ID
301787
Card Set
Hem Lec 19
Description
Hem Lec 19
Updated