VASCULAR TUMORS

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Liver angiosarcoma is associated with exposure to which carcinogens?
- Vinyl chloride- a plastic used in industry (plastic pipes)
- Arsenic - exposure to pesticides
- Thorotrast/ Thiorium dioxide- a former radioactive contrast medium used to visualize the arterial tree
How can one be exposed to vinyl chloride and what disease is at risk of developing with exposure?
- A plastic used in industry (plastic pipes)
- Liver angiosarcoma
How can one be exposed to thorotrast/ thiorium dioxide and what disease is at risk of developing with exposure to it?
- A former radioactive contrast medium used to visualize the arterial tree
- Liver angiosarcoma
How can one be exposed to arsenic and what disease is at risk of developing with exposure to it?
- Exposure to pesticides
- Liver angiosarcoma
- Lung cancer
- Squamous cell carcinoma of the skin
Describe the pathogenesis of angiosarcoma.
- Breast cancer patient ⇨ undergoes RADIATION MASECTOMY with axillary node dissection ⇨
- develops CHRONIC LYMPHEDEMA on ipsilateral arm⇨ Angiosarcoma (Stewart-Trevor syndrome)
Person develops vascular tumor after undergoing radiation masectomy for breast cancer.

Angiosarcoma
Patients with this condition are at risk for?
- Postmasectomy lymphedema
- At risk for angiosarcoma
Describe the pathogenesis of Stewart Treves syndrome.
- Breast cancer patient ⇨ undergoes RADIATION MASECTOMY with axillary node dissection ⇨
- develops CHRONIC LYMPHEDEMA on ipsilateral arm⇨ Angiosarcoma (Stewart-Trevor syndrome)
What makes Bacillary angiomatosis different from Kaposi sarcoma?
- Bacillary angiomatosis- NEUTROPHILIC INFILTRATE
- Kaposi sarcoma- LYMPHOCYTIC INFILTRATE
What is the pathology seen below?

Bacillary angiomatosis
What is this leison and what happens to it over time?
- Cherry hemangioma
- Does not regress, frequency ⇧with age
This type of vascular tumor consist of dilated capillaries and post-capillary venules in the papillary dermis.

Cherry hemangioma
Describe the findings of cherry hemangioma.
- Small, bright red cutaneous papules (in elderly)
- Consist of dialted capillaries and post-capillary venules in the papillary dermis and do not regress spontaneously
Cavernous lymphangioma of the neck is associated with?

Cystic hygroma- Turner & Down syndrome
What is a cystic hygroma and in which diseases it it found?

Tumors that are composed of lymphatic cysts (dilated lymphatic spaces) lined by endothelium
What is the pathology seen below?
- Glomous tumor-
- Painful red-blue tumor under fingernails.
- Arises from modified smooth muscle cells of the thermoregulatory glomus body
Ppt presents with bluish leison under fingernail. Leison is tender to touch. If this lesion is a tumor, where do the cells originate from?
- Glomous tumor-
- Arises from modified smooth muscle cells of the thermoregulatory glomus body
What is the function of the glomus body?
- Found in the nail beds of the fingers, toes and ears
- Shunts blood away from skin surface in cold temperatures to prevent heat loss and directs blood flow to the surface in hot environments to facilitate heat loss.
Polypoid capillary hemangioma is characteristic of?

Pyogenic granuloma
Which vascular tumor is characteristic of this histologic finding?

Pyogenic granuloma
Describe the presentation of a pyogenic granuloma.
- Red nodules attached by a salk to gingiva or oral mucosa or skin.
- Can ulcerate and bleed.
- Associated with trauma and pregnancy
- Histologically leisons resemble hypertrophic granulation tissue
What is the pathology seen below?
- Pyogenic granuloma
- Polypoid capillary hemangioma

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rere_girl4ever

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Card Set

VASCULAR TUMORS

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VASCULAR TUMORS

Updated

2015-03-16T04:13:57Z

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