Antibody Mediated Immunity

It involves the antigen-antibody interactions to neutralize, eliminate or destroy foreign proteins.

The body learns to make enough of any specific antibody to provide long-lasting immunity and protection against specific organisms or toxins.

• The Seven Steps are:
• Exposure/invasion
• Antigen Recognition
• Lymphocyte Sensitization
• Antibody Production and Release
• Antigen-antibody binding
• Antibody-Binding reactions
• Sustained immunity or memory

• Antibodies are produced by B-Lymphocytes (B-Cells).
• Antibodies causes one of several actions to neutralize, eliminate or destroy that antigen.

The main purpose of the B-cells are to become sensitized to a specific foreign protein (antigen) and to produce antibodies directed specifically against that protein.

• Starts out in the bone marrow as stem cells.
• Released into the blood and travel to secondary lymphoid tissues such as spleen, parts of lymph nodes, tonsils and mucosa of the intestinal tract.

• Macrophage recognizes the invader and attaches itself to the antigen.
• Macrophage does not attack but presents the antigen to the helper T-Cell.
• Both will process the antigen to expose the antigen's recognition sites.