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Hem Lec Ch10
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The etiology of IDA is?
nutrition deficiency
Faulty iron absorption
excessive loss of iron
Iron deficiency is still common in?
toddlers
adolescent girls
women of childbearing age
Decreased iron intake is associated with?
Meet-poor diet
Physiological iron lass is associated with?
Menstruation
Increased iron utilization is associated with?
Adolescent growth spurt
Pathological iron lass is associated with?
Colon cancer
Decreased iron intake is associated with?
Sprue
The average adult has ____g of iron
3.5g - 5.0g
Most functional iron in humans is found in?
Hemoglobin molecules of erythrocytes (RBC)
Approximately ____% of iron from food is in the form of _____ iron?
90%
Noneheme
Most ingested iron is readily absorbed into the body in the ?
duodenum
upper jejunum
Transferrin represents a?
Beta globulin that moves iron
Glycoprotein that moves iron
(Beta globulin glycoprotein)
In IDA, the erythrocytic indices are typically ?
MCV - decreased
MCH - decreased
MCHC - decreased
Peripheral blood smear demonstrates ______ red blood cells in IDA?
Microcytic, Hypochromic
Anemias of inflomation/chronic diseases can be caused by?
Inflammation
Infection
Malignancy
AOI can result from?
inappropriately decreased erythropoietin
suppression of erythropoiesis by cytokine from activated macrophages and lymphocytes
impaired iron metabolism
The typical peripheral blood film of a patient with AOI typically reveals _____ erythrocytes?
Normocytic, normochromic
Leukoerythroblastosis can appear as ______ on a peripheral blood smear?
Immature leukocytes
Immature erythrocytes
What is the most appropriate treatment for AOI?
treatment of inflammatory condition
Sideroblastic anemia can be caused by?
congenital ( chromosomal) defect
drugs
association with malignant disorders
A common feature of sideroblastic anemia is?
Ringed sideroblasts
The greatest portion of operational body iron is normally contained in what compound?
Hemoglobin
Storage Iron in a human body is?
found in Hepatocytes
found in Macrophages
sequestered as Ferritin
The most sensitive assay for the diagnosis of hereditary hemochromatosis (HH) is
transferrin saturation
in IDA, the ?
serum iron is severely decreased and the TIBC is increase
Author
CTEPBA
ID
297046
Card Set
Hem Lec Ch10
Description
Hem Lec Ch10
Updated
2015-03-06T19:30:22Z
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