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Hemoglobin.txt
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author "rmslim1"
tags "Hematology"
folders ""
description ""
fileName "Hemoglobin"
Adult hgb A
Has 4 heme groups & 4 polypeptide chains (2 alpha & 2 beta)
Function of hgb
Carry O2/CO2 to/from tissues
Heme's Oxygen affinity regulated by
2,3 DPG
P50 value =
26.52 mm/hg
>O2 affinity &
To the left
DPG O2 curve shifts
To the right
What is Transferin
Heme messenger
Hgb breakdown @ birth
HGB F 60-80% / hgb A 20-40%
Hgb breakdown for adults
HGB A 95-97% / HGB A2 2-3% / HGB F 1%
HGB affinity for CO
210x more affinity than oxygen
Fe2+ (ferrous state) is oxidized to
F3+ (ferric state)
RBC lifespan (in days)
Adult 120 / fetus 60-70 / premie 30-50
Author
rmslim1
ID
295989
Card Set
Hemoglobin.txt
Description
Hemoglobin
Updated
2015-02-16T15:57:16Z
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