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melissag94
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study of hormones
endocrinology
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released outside of body
exocrine
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released into blood stream
endocrine
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very slow and influences metabolism via chemical messages
endocrine system
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electrochemical impulses regulate muscles and glands
nervous system
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major endocrine glands
pituitary, thyroid, parathyroid, adrenal, pineal and thymus glands
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presence of a hormone causes both of these to happen
AMP and PIP
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2 types of hormones are derived from
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this type of hormone is more popular than a steroid based hormone
amino acid based (derived from protein)
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hormone that works by a secondary messenger system
amino acid based
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2 types of secondary messenger systems
- cyclic AMP (cAMP)
- PIP- calcium signaling mechanism
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type of protein and receives info from a hormone
receptor
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breaks down energy (ATP) into cAMP
adenylate cyclase
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2 messages a cell get in cAMP signaling?
- that hormone is there
- adenylate cyclase breaks down ATP into cAMP
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molecule of guanosine is attached to the protein and it is inactive until hormone binds on to the receptor
g protein
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GDP goes to GTP when
you add 3 phosphates
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may cause cell to open ion channels, but it depends on hormone and what it is designed to do
protein kinese
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why do you want more glucose in your blood stream?
so you can combine it with O2 and create more energy
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glucose + O2 ==>
co2 + H20 + ATP
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enable transcription inside the cell
steroid hormones
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has no secondary messenger system and just goes straight into the cell
steroidal hormones
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when a hormone is released, the concentration of that hormone ____, the concentration of blood will go ____
- increase
- down (down regulating)
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ex of humoral response
parathyroid hormone
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travel in blood free or bound to protein carriers
hormones
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blood hormone concentration decrease bc of
- degraded by target organs
- removal by kidneys and liver
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half life of a hormone?
seconds to 30 mins
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when the concentration of the hormone is 50% of its maximal level
half life
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half life refers to
concentration in plasma
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3 major stimuli of hormone release
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fluid in human body when Ca++ lowering causes PTH release
humoral
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nerve cell where SNS stimulates adrenal gland to release epinephrine
neural
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hypothalamus releases hormones that cause pituitary to release other hormones
hormonal (common) stumuli
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plasma changes in human body due to
change in ionic content or as a result of change in nutrient status
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releases precursor hormone
hypothalamus
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breaks down stored fat and turns it into fatty acids to make ATP
growth hormone
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2 areas particularly targeted by growth hormone that grow the most
bone and skeletal muscle
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substance released before thyroid hormone is released
precursor
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initial stimulus that acts on body temperature
hypothalamus
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controls body temperature
hypothalamus
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regulates metabolic rate
thyroid hormone
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thyroid stimulating hormone
TSH
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thyroid releasing hormone
TRH
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why is calcium needed
- bone growth
- muscle contraction
- the nervous system to communicate from 1 neuron to another
- blood clotting
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if growth hormone is down regulated, than it will create
fat
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when calcium level is too low,
pth is released
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up regulating osteoclast activity means that
calcium is released into bloodstream
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mediates process of absorbing calcium from diet through wall
PTH
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calcium goes out of kidney and back into the bloodstream
calcium reabsorption
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what allows calcium to be reabsorbed
PTH
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converts stored proteins into glucose
cortisol
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low level of plasma glucose
hypoglycemia
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series of different hormones that affect plasma glucose levels
glucocorticoids
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when body temperature goes up, what happens to the rate of ATP production?
it goes up
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take stored body reserves, convert into glucose and use
glucocorticoids
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when levels are too high of glucocorticoids, the body
down regulates cortisol production
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__ and ___ reabsorption are linked in kidneys
- salt and water
- water follows salt
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cause bronchial dilation
epinephrine and norepinephrine
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quickest way to increase blood pressure?
vasoconstrict blood vessels
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catecholamines?
another name for epinephrine and norepinephrine
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2 hormones released by the pancreas?
insulin and glucagon
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when too much glucose is released?
hypoglycemia
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in times of starvation, what happens to plasma glucose?
it goes down and the pancreas releases glucagon
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hormone that promotes birth
oxytocin
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if you drink a lot, but cant get rid of it what happens to your blood pressure?
it increases
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