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REPRODUCTIVE SYSTEMS
Male and female reproductive systems are connected by a series of organs and glands that produce & nurture sex cells & transport them to sites of fertilization
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Sex Cells
- Male = sperm
- Female = eggs or oocytes
- Sex cells are produced by a special type of division called meiosis
- Meiosis includes two successive divisions , called the first (meiosis I) and second (meiosis II) meiotic divisions
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First Meiotic Division
- Meiosis I separates homologous (the same, gene for gene) pairs
- May not be identical because a gene may have variants
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Four phases in this division
Prophase I
Metaphase I
Anaphase I
Telophase I
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Second Meiotic Division
- Meiosis II begins after telophase I
- Similar to mitosis
- This division completes with each sex cell having one set of genetic instructions, or 23 chromosomes (compared to two sets (46 chromosomes) in other cells)
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Four phases in this division:
- Prophase II
- Metaphase II
- Anaphase II
- Telophase II
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Male Internal Accessory Organs
- Epididymides
- Ductus deferentia
- Seminal vesicles
- Prostate gland
- Bulbourethral glands
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Epididymides
- Tightly coiled tubes
- Connected to ducts within the testis
- Promote maturation of sperm cells
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Ductus Deferentia
- Are muscular tubes
- About 45 centimeters each
- Extends from the epididymis to the ejaculatory duct
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Seminal Vesicles
- Attached to the vas deferens near base of the urinary
- bladder
- Secrete alkaline fluid
- Secrete fructose and prostaglandins
- Contents empty into the ejaculatory duct
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Prostate Gland
- Surrounds the proximal portion of the urethra
- The ducts of the gland open into the urethra
- Secretes a thin, milky, alkaline fluid
- Secretion enhances fluid mobility
- Composed of tubular glands in connective tissue
- Also contains smooth muscle
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Bulbourethral Glands
- Inferior to the prostate gland
- Secrete mucus-like fluid
- Fluid released in response to sexual stimulation
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Semen
- The fluid the urethra conveys to the outside during ejaculation is called semen
- Semen consists of:
- Sperm cells
- Secretions of the seminal vesicles, prostate gland, & bulbourethral glands
- Is slightly alkaline
- Contains prostaglandins
- Contains nutrients
- Volume is 2-5 milliliters of semen per ejaculation
- Average 120 million sperm cells per milliliter of semen
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Male External Reproductive Organs
- Includes the:
- Scrotum (and two testes)
- Penis
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Scrotum
- Pouch of skin and subcutaneous tissue
- Dartos muscle – smooth muscle in subcutaneous tissue; contracts to cause wrinkling of the scrotum
- Medial septum divides the scrotum into two chambers
- Each chamber is lined with a serous membrane
- Each chamber houses a testis and epididymis
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Penis
- Conveys urine and semen
- Specialized to become erect for insertion into the vagina
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Erection, Orgasm, and Ejaculation
- The erection:
- Parasympathetic nerve impulses
- Blood accumulates in the erectile tissues
- The orgasm:
- Culmination of sexual stimulation
- Accompanied by emission and ejaculation
- The ejaculation:
- Emission is the movement of semen into the urethra
- Ejaculation is the movement of semen out of the urethra
- This is largely dependent on sympathetic nerve
- impulses
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Hormonal Control of Male Reproductive Functions
- Hormones secreted by the hypothalamus, the anterior pituitary gland, & the testes control male rep. functions
- Hormones initiate and maintain sperm cell production & oversee the development and maintenance of male sex characteristics
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Hypothalamic & Pituitary Hormones
- The hypothalamus controls maturation of sperm cells & development of male secondary sex characteristics
- Negative feedback among the hypothalamus, the anterior lobe of the pituitary gland, and the testes controls the concentration of testosterone
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Male Sex Hormones
- The male sex hormones are called androgens
- Interstitial cells in the testes produce most of them, but small amounts are made in the adrenal cortex
- Testosterone is the most important
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Actions of Testosterone
- Increased growth of body hair
- Sometimes decreased growth of scalp hair
- Enlargement of the larynx and thickening of the vocal cords
- Thickening of the skin
- Increased muscular growth
- Thickening and strengthening of the skeletal bones
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Ovary Attachments
- Several ligaments hold each ovary in position
- The largest is called the broad ligament and is attached to the uterine tubes and uterus
- The suspensory ligament holds the ovary at the upper end
- The ovarian ligament is a rounded, cord-like thickening of the broad ligament
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Ovary Descent
- Like the testes in the male fetus, the ovaries develop from masses of tissue posterior to the parietal peritoneum, near the developing kidney
- They descend to locations just inferior to the pelvic brim where they remain attached to the lateral pelvic wall
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Ovary Structure
- The tissues of an ovary can be divided into an inner medulla and an outer cortex
- The ovarian medulla is mostly composed of loose connective tissue and contains many blood vessels, lymphatic vessels, and nerve fibers
- The ovarian cortex consists of more compact tissue & has a granular appearance due to tiny masses of cells called ovarian follicles
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Primordial Follicles
- During prenatal development of a female, oogonia divide by mitosis to produce more oogonia
- The oogonia develop into primary oocytes
- Each primary oocyte is closely surrounded by a layer of flattened epithelial cells called follicular cells, forming a primordial follicle
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Follicle Maturation
- At puberty, the anterior pituitary gland secretes increased amounts of FSH, and the ovaries enlarge in response
- With each reproductive cycle, some of the primordial follicles mature
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Follicle Maturation
- As many as twenty primary follicles may begin maturing at any one time
- One dominant follicle usually out-grows the others
- Typically only the dominant follicle fully develops & the others degenerate
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Ovulation
- As a follicle matures, its primary oocyte undergoes meiosis I, giving rise to a secondary oocyte
- & a first polar body
- The process of ovulation releases these cells from the follicle
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Female Internal Accessory Organs
- The female internal accessory organs include:
- Uterine tubes
- Uterus
- Vagina
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Vagina
A fibromuscular tube that conveys uterine secretions, receives the penis during intercourse, and provides an open channel for offspring
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Female External Reproductive Organs
- The female external reproductive organs surround the openings of the urethra and vagina and is known as the vulva, and include:
- Labia majora
- Labia minora
- Clitoris
- Vestibular glands
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Labia Majora
- Rounded folds of adipose tissue and skin
- Enclose and protect the other external reproductive parts
- Ends form a rounded elevation over the symphysis pubis
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Labia Minora
- Flattened, longitudinal folds between the labia majora
- Well supplied with blood vessels
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Clitoris
- Small projection at the anterior end of the vulva
- Analogous to the male penis
- Composed of two columns of erectile tissue
- Root is attached to the sides of the pubic arch
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Vestibule
- Space between the labia minora that encloses the vaginal and the urethral openings
- The vestibular glands secrete mucus into the vestibule during sexual stimulation
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Hormonal Control of Female Reproductive Functions
- Hormones secreted by the hypothalamus, the anterior pituitary gland, and the ovaries control development
- & maintenance of female secondary sex characteristics, maturation of female sex cells, & changes during the monthly reproductive cycle
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Menopause
- Usually occurs in the late 40s or the early 50s
- The reproductive cycles stop
- The ovaries no longer produce as much estrogens & progesterone as previously
- Some female secondary sex characteristics may disappear
- It may produce hot flashes and fatigue
- Migraine headaches, backaches and fatigue is possible
- Hormone therapy may prevent effects on bone tissue
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Mammary Glands
The mammary glands are accessory organs of the female reproductive system specialized to secrete milk following pregnancy
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Location of the Glands
- Located in the subcutaneous tissue of the anterior thorax within the breasts
- Composed of lobes
- Estrogens stimulate breast development in females
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Structure of the Glands
- A mammary gland is composed of fifteen to twenty irregularly shaped lobes
- Each lobe contains glands (alveolar glands), drained by alveolar ducts, which drain into a lactiferous duct that leads to the nipple and opens to the outside
- Dense strands of connective tissue form suspensory ligaments that support the breast
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Development of the Breasts
- The mammary glands of males and females are similar
- As puberty is reached, ovarian hormones stimulate development of the glands in females
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Birth Control
- Birth control is the voluntary regulation of the number of offspring produced and the time they are conceived
- This control requires a method of contraception
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Coitus Interruptus
The practice of withdrawing the penis from the vagina before ejaculation, preventing entry of sperm cells into the female reproductive tract
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Rhythm Method
Requires abstinence from sexual intercourse two days before and one day after ovulation
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Mechanical Barriers
- Condom
- Diaphragm
- Cervical cap
- Spermicidal foams or jellies
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Chemical Barriers
Spermicides
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Combined Hormone Contraceptives
- These deliver estrogen and progesterone to prevent pregnancy
- Various methods are used to deliver hormones including:
- Flexible chemical ring (Nuvaring)
- Plastic patch (Ortho Evra)
- The pill orally
- (Similar to these combined hormones is the “minipill” which contains only progestin)
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Injectable Contraception
An intramuscular injection of Depo-Provera protects against pregnancy for three months by preventing maturation and release of a secondary oocyte
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Intrauterine Devices
- An intrauterine device, or IUD, is a small, solid object that a physician places in the uterine cavity
- An IUD interferes with implantation of a blastocyst
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Sexually Transmitted Diseases
- These are silent infections
- Most are bacterial and can be cured
- Herpes, warts, and AIDS are viral and cannot be cured
- Many cause infertility
- AIDS causes death
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Symptoms of STDs include:
- Burning sensation during urination
- Pain in the lower abdomen
- Fever or swollen glands
- Discharge from the vagina or the penis
- Pain, itch, or inflammation in the genital or the anal area
- Sores, blisters, bumps or rashes
- Itchy, runny eyes
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Pregnancy, Growth, and Development
- A sperm and a secondary oocyte unite, forming a zygote, and the journey of prenatal development begins
- After 38 weeks of cell division, growth and specialization into distinctive tissues and organs, a new human being enters the world
- Humans grow, develop and age
- Growth is an increase in size
- Development, which includes growth, is the continuous process by which an individual changes from one life phase to another
- – Prenatal period is from fertilization to birth
- – Postnatal period is from birth to death
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Pregnancy
- Pregnancy is the presence of a developing offspring in the uterus
- It consists of three periods, or trimesters, each three months long
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Transport of Sex Cells
- Before fertilization can occur, a secondary oocyte must be ovulated and enter a uterine tube
- Only 200 of between 200 to 600 million sperm reach a secondary oocyte
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Fertilization
Fertilization is the union of an egg cell (secondary oocyte) & a sperm cell
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