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What is the Ductus Venosa
Connects the umbilical vein to the fetal inferior vena cava (IVC)
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What causes the blood to by pass the liver?
The Ductus Venosus
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When does the Ductus Venosus close?
about 1 week of age
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Most of the red blood goes across the
PFO
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What connects main pulomary artery (PA) to the descending aorta (Ao)?
ductus arteriosus
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What diverts blood away from the lungs
Ductus Arteriosus
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The muscular structure of the ductus arteriosus is about
10 mm in diameter
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Functional closure of the Ductus Arteriosus occurs when
3-4 days
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Anatomic closure of the Ductus Arteriosus occurs when ?
around 2 months
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After birth, what can reopen the Ductus Arteriosus?
hypoxemia or an increase in porstaglandins E1
IMPORTANT
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Patent Forman Ovale
Flab between the right atrium and left atrium
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Blood shunts across from right to left atrium through what?
Patent Foramen Ovale
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________________ often persists in infancy, especially in NAS babies, of no consequence, called "normal for age"
PFO
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Impediment to blood flow through a vessel
vascular resistance
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Pressure as measured by the size of the arteries and arterioles in the pulmonary vascular bed
pulmonary vascular resistance (PVR
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Pressure as measured by the size of the arteries in the peripheral vascular bed
Systemic vascular resistance (SVR)
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Flow goes where?
resistance is lease
IMPORTANT
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Resistance is governed by
the size of the blood vessels (size of the vessel dictated by the muscularity
IMPORTANT
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In newborns, the _________ is the dominant pumping chamber
RIGHT
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Respiratory distress is associated with
heart failure
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PVR and SVR in Fetus
PVR is high because you dont want blood to go to the lungs, want it to go to the body
PVR drops when they are born so the lungs can get blood, SVR rises
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Fetal breathing movements begin at
11 weeks
she skipped slide in class
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In fetal lungs, pulmonary arterioles are ________
constricted
she skipped slide in class
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Fetal lung fluid is secreted by the lungs and decreases when?
as term approaches
she skipped slide in class
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The fetus breathes in and out fetal lung fluid through
the trachea
she skipped slide in class
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Once the Cord is clamped.........
Infant cries
Supply from placenta is abruptly cut
Umblical veins and arteries constrict
Blood no longer flows through the fetal circuit
Sudden increase in SVR
she skipped slide in class
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Neonatal Circulation
DA closes ( increase in pO2) and abesence of prostglandins
PFO shuts (SVR rises---> LA rises and slams shut PFO)
PFO is later sealed by fibrin
Often PFO persists in neonatal period (no significance)
PFO Can reopen if RA pressure incraseas significantly
she skipped slide in class
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When the PFO shuts after birth , SVR rises and the
Left atrium rises and slams shut PFO
she skipped slide in class
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What seals the PFO
fibrin
she skipped slide in class
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If the PFO persists in the neonatal period, is something wrong?
No
she skipped slide in class
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When can the PFO reopen
If the Right Atrium pressure increases significantly
she skipped slide in class
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