-
Who over sees the care and use of animals?
IACUC
-
What guidelines do the IACUC use?
AWR and PHS
-
If fluids are restricted how often must you way the animal?
At least once a week (twice for rodents)
-
What is a Micro and Macro environment?
- Macro - Room
- Micro - Kennel/Cage
-
What is Thigomotactic, and what species prefers it?
Mice: They prefer more wall space than floor space
-
What is the lighting lux and noise dB max?
325lux and 85dB
-
At what temp will food start detreriate?
21C
-
why is cedar shavings looked down upon?
emit aromatic hydocarbons that effect liver enzymes
-
What two zoonotic diseases are from non-human primates?
Filovirus and mcobacterial
-
What intra-species disease is carried in rabbits?
Bordetella brochiseptica
-
Subclinical infections in rodents are? (5)
Sendai virus, kilham rat virus, mouse hep virus, lymohocytic choriomeningitis virus, mycoplasma pulmonis
-
Animal Room Doors measurements are...
~42in W and ~84in H
-
Humidity levels should be where?
30-70% with a 5% variation
-
Lighting should be on what system in animal rooms?
time-contolled diurinal lighting cycle
-
What members are necessary fro the IACUC?
Veterinarian, public member, and scientist
-
IACUC acronym stands fro what?
Institutional Animal Care Use Committee
-
Animals adapt to extreme temps by what three methods?
Physical, morphological, behavorial
-
What kind of cage do rodents like?
Solid bottom with bedding
-
How many air changes per hour in an animal room?
10-15
-
What animal helped determine illumination levels?
albino rats
-
What is susceptiable to animals due to high room illumination levels?
Phototoxic retinopathy
-
When should bedding changes not be performed?
Pre- and Postpartum (child birth)
-
How often should solid bottoms and accessories be sanitized?
once a week for the cage and once every two weeks for accessories
-
What is the effective temp range for a quality sanitation?
143-180F
-
What animal produces large amounts of proteins and minerals in their urine?
Rabbits
-
Which type of rodent has high levels of homozygosity?
Inbred
-
Subclincial diseases are most common in what kind of rodents?
conventionally housed
-
What are corridor widths in facility?
6x8 ft
-
What should the floors be made of?
Monolithic
-
What type of walls help eliminate noise?
Masonary
-
A Class-A dealer is....
raise and sell purpose-bred species
-
A class-B dealer is...
provide random source animals
-
How must dogs (and cats) be housed?
Not outdoors, 45-85F, 6in higher than dogs tallest head [(L+6)^2/144=floor space]
-
What is the temp range for the housing of guinea pigs and hamsters?
60-85F
-
What is the temp range for housing rabbits?
40-90F
-
What is the temp range for primates?
45-85F
-
When air transporting primates, what must the container label say?
Live Animals: Wild Animals
-
USDA and IACUC inspect how often?
USDA, annually; IACUC, semiannually
-
USDA tags do not have which of the following: USDA letter, state identifier, id number, date of birth.
date of birth
-
How do you id pus under 16 weeks?
ear notching
-
How long must pass before a USDA number can be reused?
5 years
-
What is the earliest a vet can do a health examination before transportation?
10 days
-
How long must an animal wait to be used in research when obtained by random source?
5 days
-
How often must dogs be exercised, or reviewed to exercise if exempted previously?
Once a day; 30 days
-
Minimal height for a guinea pigs cage is...
7in
-
Interior height of hamster cages must be at least how many inches?
6in
-
how long can temps exceed ranges before a deviation accurs?
4 hours
-
What is the minimum height for a rabbits cage?
14in
-
Rabbits sanitations are how many days before the next?
30 days
-
What is the max amount of rabbits in one inclosure while transporting?
15
-
What does APHIS stand for?
animal and Plant Health Inspection Service
-
How many principles are there for animal research?
9 Principles
-
PHS policy mandates animal care programs to be in accordance with what three laws?
AWA, the "Guide", and AVMA
-
How often must an assurance report be done for the "Guide"?
Every 5 years
-
What is a category 1 institute?
Accredited by the AAALAC and all facilities evaluated every 6 months
-
What is the difference from a category 2 institute from a category 1?
Evaluated by the institute, and most recent report submitted to assurance.
-
How many members at lest does the IACUC need?
5 members. One DVM, one scientist, and one public member
-
What does the IACUC consider an animal facility?
The holding of animals >24 hours
-
Who shall the IACUC notice for approved/disapproved projects?
the investigators and the institution
-
If the IACUC suspends a project that was already approved who do they contact?
IO and IACUC will review then send to OLAW
-
How long must records be kept?
3 years
-
How often must IACUC report to OLAW
At least every 12 months?
-
What agencies does the PHS consist of?
Substance abuse and mental health services, health resources and services, Indian health services, NIH, and CDC
-
When exceptions to laws and guides, who must approve?
IACUC
-
How often must approved projects be reviewed?
3 years
-
Who bears ultimate responsibility for non clinical lab studies?
Sponsor
-
Who is responsible for the overall conduct of a nonclinic study?
Study Director
-
What records are exempt from FDA inspections?
QA Unit
-
How long must raw data, records, and documentations be stored?
10 years minimum
-
Who is authorized to inspect a facility and records to be maintained?
FDA and EPA
|
|
