Pathology Glossary

without, or lack of

localized collection of pus in a cavity in tissue

failure of relaxation of smooth muscle fibers

absence of hydrochloric acid secretion by stomach

relatively serious and severe; having a brief course

an acute nonsuppurative inflammatory disease of all glomeruli of both kidneys

malignant tumor arising in glandular epithelium

benign tumor arising in glandular epithelium

ability to remain together; also, scar tissue joining two parts that are usually separate

failure of formation of a body part

altered capacity to react, especially in regard to a foreign protein

a disease characterized by extracellular deposition in connective tissue of a carbohydrate protein material, amyloid

exaggerated or unusual reaction of the organism to foreign protein

accumulation of fluid in cellular tissues of body; diffuse edema

reduction of deficiency of blood either in quantity or in quality

sac full of blood formed by dilation of the walls of an artery or veing

choking or suffocating sensation or pain

a tumor of blood vessels

pneumoconiosis or lung-dust disease due to inhalation of coal pigment; coal pigmentation

new protein produced by organism in response to foreign protein or other material combining with protein, i.e., antigen

foreign protein or material capable of combining with protein which causes body to form a new protein, the antibody

absence of urine production

pigmentation due to silver salt

group of arterial diseases characterized by thickening of the vessels, frequently with hardening and/or calcification

inflammation of a joint

characteristic myocardial connective tissue change in Rheumatic Fever, cellular collection of mononuclear and giant cells around focus of fibrinoid necrosis

accumulation of fluid in peritoneal cavity

suffocation; anocia with increase of CO2

incomplete expansion, espeically in the lungs

lesion produced in intima of arteries with focal accumulation of lipids, complex carbohydrates, proteins, blood and blood products, firborus tissue, and calcium deposits and associated with changes in media

absence or closure of a normal body opening

decrease in size of cell, tissue, organ, part of or the whole body

prefix relating to self or to same individuals, e.g. autograph- transplantation of tissue from one part, to another part of the same individual.

literally self-lysis; a series of changes following death of an organism

proesence of bacteria in the blood

not harmful, not malignant

chronic dilation of bronchi

inflammation of the bronchi

body-wasting plus anemia

deposition of calcium from blood and other body fluids

concretion occuring within organism, made up in whole or in part of mineral salts

distention of superficial veins of abdomen centering on umbilicus as collateral circulation in portan vein obsturction

compound necrotizing inflammation of skin and subcutaneous tissues, usually due to staphylococcal infection

cancer-producing substance of force

argentaffin tumor, usually in intestinal tract

malignant epithelial tumor

malignant epithelia cells within normal confines of limits in the body; preinvasive carcinoma

type of necrosis in which involved tissues resembles cheese grossly

wax- like material found as crystals in disease states

damage to joint following nerve injury, as in tabes dorsalis

cellular phenomenon of moving toward or away from a certain material.

prefix referring to cartilage

convulsive nervous movements; both involuntary and irregular

tending to long course; opposite of acute

hardening, usually of the liver

strain of cells deriving from single cell

process of changing into or being changed into a clog

depressed consciousness with absence of response to stimuli

transfer of information

capable of coexistence without injury

quality of duration; existence over a serial period of time

that which directs, checks or restrains

pulmonary heart disease; disease of the heart secondary to disease of the lungs or their vessels

epithelia proliferation in space of Bowman's capsule in subacute and chronic glomerulonephritis

one whose physical and mental development has been retarded or arrested due to thyroid deficiency

blueness of the skin, or other part of the body, due to insufficient oxygen

sac containg usually a fluid or semisolid material

inflammation of the urinary bladder

prefix meaning away from

statement of the precise nature of a thing or meaning of a word

retrogressive changes of cells short of necrosis

series of changes characteristic of an organism, including existence over a serial period of time, growth and acquisition of new properties

literally "passing through"; increased uring output: diabetes mellitus and insipidus

determination of the nature of a condition or disease or a hypothetical concept concerning this

process by with a cell acquires specialized features; as applied to neoplasms, degree to which the neoplasm resembles its normal tissue counterpart in appearance and/or function

literally lack of comfort; anything that limites life in its powers, duration, or enjoyment

pouch or pocket leading off from a main cavity or tube

phagocytic cells of lung containing inhaled particles

inflammation of intestines, with blood and mucus in frequent bowel movements

convulsions occuring in last three months of pregnancy associated with placental, renal and hepatic lesions

accumulation of fluid in body or part of body beyond normal amounts

formed material circulating in the blood stream during life and coming to rest, blocking a vessel

air in tissues causing swelling

pus in a tissue space, ex: plueral cavity

inflammation of the brain

having an affinity for eosin; staining pink in H&E stain, ex: eosinophil leukocyte

disease affecting more than usual number of people in a community at one time

cell resembling epithelium usually deriving from macrophage or histiocyte

disease affecting more than usual number of animals in a group at one time

reddening and inflammation of skin, usually due to streptococci, associated with constitutional symptoms

study of the cause of disease, or the cause of disease

unusual protrusion of the eyeball

death of fatty tissue, usually result of spill of pancreastic lipase, trauma, etc

intestinal concentration fromed around or from feces

activity which contains within itself cessation or stoppage

body temperature above normal, or (old) disease so characterized

tissue material resembling fibrin found especially in collagen disease

term for uterine fibroleiomyoma

deep ulcer often communiating with an internal organ

cells with vacuolated cytoplasm, usually containg fat droplets in vaculoes

break in bone; occasionally of some other structure, eg: liver or spleen

nocular staphylococcal inflammation of skin, often in relation to hair follicle or sweat gland; the common boil.

ischemic (coagulative) necrosis of an extremity or of the appendix. When there is superimposed bacterial infection, the term "wet gangrene" may be used

multinucleated large cells; found frequently in inflammation in late stages around foreign materials as Langhans' giant cell

complex neutral polysaccharide, the storage carbohydrate of animals.

sugar in urine

enlargement of thyroid gland

disturbance of purine metabolism causing urate deposits in joints and cartilages and arthritis symptoms

a transplanted piece of tissue

aggregate of epitheloid histiocytes

local lesion of tertiary syphilis with soft tumor-like formations, histiocytes

tumor-like collection of excess tissue or abnormally situatied tissue formed during development

see REPAIR

hemosiderin-containing macrophages in lung or sputum, resulting from escape of blood into alveoli

brown to black pigment in tissue resulting from hemoglobin breakdown but not giving Prussian blue reaction of hemosiderin

accumulation of blood within a tissue (outside of a vessel)

disorder of iron metabolism with excessive iron absorption; deposited iron produces cirrhosis of liver and pancreatic damage with diabetes mellitus

brown pigment not containing iron found in the liver with hemosiderin in hemochromatosis

familial disease appearing in males, transmitted by females, characterized by absence of specific globulin in blood and imperfect coagulation

extravasation of blood into extravascular space

iron containing crystalline ferritin complex

liver disease characterized by degeneration and regeneration of liver cells and (replacement) fibrosis

protrusion of tissue through an opening

piece of tissue transplanted from one species to another

quality of tending to uniformity or stability

piece of tissue transplanted from one animal to another of the same species

literally glassy; used to describe homogenous amorphous deposits and materials

prefix denoting water, in excess

dilation of kidney by urine accumulation

prefix meaning excessive, above or beyond

increase in size of a part due to increase in number of units

increase in size of a part due to increase in cell size

prefix meaning below, inferior, lacking

jaundice

condition of being immune

characteristic intracellular (nuclear or cytoplasmic) body found especially in cells affected by viruses

specificity; quality of possesing separate identity

brought about by some means; not natural

necrosis of tissued due to ischemia

presence of pathogenic organisms in body and their effects; entrance of pathogenic organisms into body

material in tissue not normall present

local cellular and vascular reaction to injury

sert of facts concerning the state of a sorce

harm or damage; produced disturbance of structure and/or function

in spaces of a tissue; relating to such spaces

passage of one portion of intestine into an adjacent portion

entrance of material into abnormal situation

descrease in blood supply to cells or tissue

piece of tissue transplanted from one animal to another genetically related animal

suffix meaning inflammation

yellow appearance of skin, mucosa, and conjunctives, and all organs, due to excess bilirubin in serum or organs

rickettsia-like bodies in strain of paramecia injuring other paramecia of same strain which do not possess kappa particles

prefix relating to the nucleus

fading of nuclear chromatin related to enzymatic degradation of the DNA

nuclaer breakdown with residual granules

skin tumor or mass specifically following wounding or injury

hunchback; dorsal durvature of the spine

multinucleated large cell formed in relation to foreign material or bodies

characteristic change in organism produced by disease

malignant proliferation of white blood cells

reaction resembling leukemia; extreme leukocytosis of normal cells

reduction in number of circulationg leukocytes

pneumococcal infection of one or more lobes of one or both lungs

specific disease of skin with tissue destruction and sometimes systemic lesions of collage

inflammation of lymph nodes

edema due to lymphatic obstruction

softening of tissue in desease ex: encephalomalacia, osteomalacia

tendency of a neoplasm to infiltrate and metastasize

pigment granules, usually black, derived from indole and present in animals.

the passage of dark, pitchy, and grumous stools stained with blood pigments or with altered blood

replacement of one type of cell in tissue by another

resembling a millet seed; marked by multiple small lesions barely visible to the naked eye

tumor or neoplasm made up of one or more than one cell or tissue type

accumulation of mucus with cyst formation, as in appendiz

disease due to thyroid deficeincy characterized by deposition of excess ground substance in subuctaneous tissue and viscera

occuring spontaneously; not made, brought about or induced

death of cells

process of new growth or tumor formation

destruction of nerve cells by phagocytic action, as in acute anterior poliomyelitis, etc

new growth of skin, usually containing nerve elements, also congenital dilation of blood vessels in part of skin

process of passing out of existence or becoming obsolete

something that impedes or blocks a flow

decrease in urine volume

ingrowth of fibroblasts and endothelial cells into a fibrinous exudate, converting it to a scar, or into a thrombus, converting it to a fibrous plug with variable re-canalization of the vessel lumen

projecting from a surface

benign epithelial neoplasm often composed of finger-like projections fron an epithlial surface

prefix meaning behind, eg para-appendiceal

loss or decrease of ability to move

an organism that lives on or withing another without itself contributing

slight or partial paralysis

disease producing agent

development of a morbid condition or disease

the biological discipline which studies disease (or studies life in its abnormal forms and activities)

literally rough skin; clinical syndrome due to niacin deficiency, characterized by diarrhea, dermatitis, and dementia

related to digestion

a piercing or making a hole, as in a viscus

prefix signifying around, eg periarteritis: inflammation around the artery

cell of the body that ingests particulate matter

a wasting away (or a part of the body); vernacular for pulmonary tuberculosis

any dye or paint; any natural or abnormal coloring matter of the body

inflammation of lungs, usually with consolidation and systemic symptoms

localized inflammation of lungs

substance cabable of interfereing with metabolic processes of a cell or part of cell, of a tissue, organ, or organism

excess of erythrocytes

benign or malignant neoplasm producing a visible projection above a mucosa surface, often into a lumen

like a polyp, projecting from a surface

series of changes

prediction of probably outcome and/or course of a disease

condition with confluent small hemorrhages over body surfaces

liquid material containg brocken down leukocytes and cells; usually resulting from inflammation

inflammation of pelvis and interstitial tissue of the kidney

septicemia with pus in blood and secondary sites of suppuration

prefix meaning pus

fever, temperature above normal

pus in the urine

(emission of) waves or rays of heat, light, x-ray, or other radioactive materials

renewal of lost tissue or parts

restoration of continuity after injury

relating to inflammation of joints or rheymatism

rigidity or stiffness

malignant tumor of mesenchymal tissue

remnants or residuum of the healing process

prefix meaning hard

epithelial tumor arising in the testes

with broad base of attachment

severe depression of bodily activities caused by infection, hemorrhage, trauma, etc.

any objective evidence of disease

that which affects a receptor; information

pathologically, a suppurating channel or fistula

particles in suspension in viscid fluid; settling out equals sludging

sudden violent involuntary constriction of muscles or sudden transitory constriction of a canal, passage or opening.

excess of fat in stools; fatty stools

narrowing of a duct, canal or channel or a natural passage

less than completely acute, between acute and chronic

any functional evidence of disase or of a patient's condition

a set of symptoms that occur together

wasting or atrophy or a part, e.g. tabes dorasalis or atrophy of dorsal spinal columns in late syphilis

type of thinking emphasizing purpose interpretation of structure and function

pattern, mould, or guage determinig configuration of structure

blood clot formation within intact vessel

accepted without reaction or without usual reaction

collection or urates in tissues in gout

exchange of fluid between two organisms; blood transfusion, lymph transfusion

exchange of tissue between two oranisms

circulation or movement of materials

injury or wound

involuntary trembling or quivering

small nodule, usually rleated to or caused by M. tuberculosis

literally any swlling of a part; usually a neoplasm

lack of continuity of a mucous or cutaneous surface

excess urea in blood; symptom complex of renal failure

enlarged and dilated vessel, usually tortuous, usually in vein

small collection of fluid, eg: sunburn vesicle

intestinal ostruction due to twisting of bowel

restoration of continuity after wounding

literally yellow substance; subcutaneous collection of cholesterol and foam cells

literally dry eye; atrophic conjunctivitis from vitamin A deficiency.