Syphilis 6.3

Syphilis is caused by a spirochete bacteria called what?

direct examination of treponema is performed with:

what type of motility does T. pallidum have?

T. Pallidum has _ to __ coils that are _ to __ um long.

true or flase
T. Pallidum is not grown on cultivated media

this varient of T. pallidum is found in eastern Mediterranean, the Balkans and cooler areas of North Africa.

this disease is caused by T. pertenue and is found in the carribean, latin america, central africa and the far east.

This disease is caused by T. carateum and found in latin america, and infection is limited to skin.

what is the name of the lesion that develops at the point of inoculation in syphilis.

how often is the Chancre located around the genitalia?

Chancre will persist for ______ weeks and will be healed in _______ weeks.

how long after the appearance of the chancre does symptoms of secondary syphilis occur.

Secondary syphilis has symptoms of a _________ _________.

in what stage of syphilis does lyphadenopathy and skin lesions on the hands and feet occur.

secondary syphilis will resolve itself in how many weeks even without treatment?

Latent syphilis occurs when.

after four years of latency _______ are rare.

this stage of syphilis is characterized by the presence of destructive granulomas called gummas.

in what stage of syphilis do spirochetes involve brain tissue causing paresis, personality changes, dementia, and delusional states.

this is caused by maternal spirochetemia and transplacental transmission of microorganism.

late congenital syphilis may manifest what two signs and symptoms?

saddle-nose deformity is seen in what type of syphilis.

these tests are designed to detect Reagin, an antibody-like substance.

this is a carbon particle antigen used to detect the presence or reagin.

what are the two nontreponemal tests?

these are used to confirm a reactive non treponemal test.

Treponemal tests are used to detect the presence of what?

Treponemal tests use what to detect T. pallidum antibodies?

what are the two treponemal tests?

in RPR if reagin is present __________ occurs

what is the minimum amount of serum needed to perform an RPR test?

how are RPR specimens stored?

how long is unopened RPR antigen stable for?

how long is opend RPR antigen stable for if refrgerated at 2-8^oC.

what gauge needle is used to perform RPR testing?

The needle used for RPR should deliver what amount of antigen per mL.

what quantity of serum do the RPR Dispenstirs delvier?

At what speed should the rotator rotate if performing RPR testing.

what three things should be performed prior to RPR testing?

medium to large agglutination in an RPR result is called ________.

no agglutination in an RPR result is considered _________.

slight agglutination in RPR result is considered __________.

in what test is a patient's serum heat inactivated and mixed with a buffered saline suspension of cardiolipin-lecithin-cholesterol antigen.

in VDRL how is the mixture examined for flocculation.

what is the rotator speed when performing VDRL?

This is the most sensitive serological procedure in the detection of primary syphilis.

FTA-ABS has ____ sensitivity in diagnosing tertiary (late) syphilis.

in FTA-ABS a patient's heat inactivated serum is allwed to react with an extract of ___________ that has been fixed to the slide

How is serum heat inactivated?

what is added to slide so the antigen antibody reaction is visible in FTA-ABS?

what does AHG bind with if the FTA-ABS reaction is present?

If T. pallidum antibodies are present in FTA-ABS, what will the slide look like?

in what test are red blood cells sensitied with T. pallidum?

in MHA-TP, if antibody is present, it will bind to antigens causing what?

if positive what will be the appearance of the micro-dilution well in MHA-TP?

if negative what will the appearance of an MHA-TP sample be?