The flashcards below were created by user thedewhub on FreezingBlue Flashcards.

  1. regional seizures in the brain
    Partial or local seizures -
  2. global involvement of the brain in a seizure
    Generalized seizures -
  3. {10%} cortical focal [Phenytoin, Carbamazepine, Valproate, newer Lamotrigine, Levetiracetam, Topiramate, Oxcarbazepine, Zonisamide] patient is conscious and aware 2. highly localized; minimal spread motor cortex - one limb jerking visual cortex - light flashes or colors somatosensory ctx. - tingling or numbness
    Simple partial seizures
  4. psychomotor epilepsy-[Carbamazepine, Phenytoin, Valproate,newer Lamotrigine, Levetiracetam, Topiramate, Oxcarbazepine, Zonisamide], usually bilateral limb involvement, altered level of consciousness doesn’t fall to the ground - just unaware, most difficult to treat pharmacologically***
    Complex partial seizures -
  5. {10%} partial seizure preceding a tonic-clonic attack with convulsions. [Phenytoin, Carbamazepine, Valproate newer Lamotrigine, Levetiracetam, Topiramate,Oxcarbazepine, Zonisamide]
    Partial seizures secondarily generalized
  6. [Ethosuximide > Valproate or Lamotrigine] usually children, blank stare, 10 sec
    Absence (petit mal) seizures
  7. [Valproate, Lamotrigine]sudden stiffening, frequently fall backwards, loss of consciousness
    Tonic seizures
  8. [Valproate, Lamotrigine] sudden loss of postural tone, usually fall forward
    Atonic seizures
  9. [Valproate, Lamotrigine]
    Clonic and myoclonic seizures
  10. [Lorazepam, Diazepam, Phenytoin and/or Propofol]A continuous seizure state that can be fatal.
    Status epilepticus
  11. is a heterogeneous group of disorders characterized by RECURRENT seizures.

    • Drug of choice for generalized seziures in children
    • Carbamazepine
  12. Is physically addictive
  13. Not used in breastfeeding due to possible liver toxicity
    Valproic acid
  14. 3rd line drug-recommended in patients that didn’t respond to other drugs and the epilepsy is so severe that additional risk is deemed necessary
  15. Gingival hyperplasia and increase in body hair/hirsutism
  16. Phenytoin that is given IV
  17. How are the new drugs usually eliminated from the body? Liver or kidney
  18. D/C if rash develops, and how do you prevent rash from occurring
    Lamotrigine. Give drug slowly.
  19. Visual field defects in 1/3 of patients delayed FDA approval in US
  20. Inducers of microsomal enzymes (3) and what does this mean?
    Carbamazepine, phenytoin, phenobarbital ….idk what it means
  21. Has the longest half-life
  22. Is an adjunct therapy with partial seizure
  23. For Catamenial epilepsy
  24. Aplastic anemia risk (2)
    Carbamazepine, Felbamate
  25. Lamotrigine-liver or kidney?
  26. Use with extreme caution in renal failure patients
  27. Replaced gabapentin
  28. When should IV drugs be administered in status epilepticus
    After 30 min of cont. seizure
  29. Decreased effectiveness of OCP (4)
    Topiramate, Phenytoin, Carbamazepine, phenobarbital
  30. Increased spina bifida risk (2)
    Carbamazepine (10X) Valproic Acid (20X)
  31. For Lennox –Gousttaut and what is this?
    Rufinamide. d/o of multiple diff seizure types
  32. Drug of choice for absence seizures
  33. Drug of choice for Status Epilepticus? What else can be used? Why is this not drug of choice?
    Diazepam or Lorazepam. Phenytoin/Fosphenytoin can be used but doesn’t act as quickly
  34. Must participate in a special program-lots of paperwork
  35. Universal drugs (2)
    Valproic acid, Lamotrigine
  36. What do you give if status epilepticus isnt being controlled after 1 hr and you already gave 1st line drugs
  37. May temporarily suppress WBC counts
  38. What drug do you give for status epilepticus if you don’t have control after 2nd line drug?
    Propofol (IV)
  39. Should a pregnant lady take antiseizure meds

    • Drug of choice in febrile infant seizures and why
    • Phenobarbital – because it is easily absorbed
  40. Steady state stabilized quickly
    Levetiracetam (leve=level=levels/steady quickly)
  41. May aggravate absence seizures
  42. Can raise phenobarbital levels by 40%
    Valproic acid
  43. Drug and route of administration for treating status epilepticus out of the hospital
    Diastat-rectal form
  44. Has minimal effects on behavior and therefore is OK in children
    Valproic acid
  45. Which drug is <1% bound
  46. Must monitor blood levels
  47. Can produce Kidney stones (2)
    Topiramate Zonisamide
Card Set
Show Answers