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central nervous system (CNS)
- brain and spinal cord
- responsible for interpreting incoming sensory info and issuing instructions
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peripheral nervous system (PNS)
somatic (voluntary) and automatic (involuntary) nervous systems
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neuron
basic cell of the nervous system
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dendrite
impulses TO cell body
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axon
impulses FROM cell body
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synapse
- junction where nerve impulses move from one neuron to another
- assisted by neurotransmitters
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afferent neurons
sensory - carry impulses from skin/muscles to CNS
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efferent neurons
motor - carry impulses from CNS to muscles/glands
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myelin sheath
- fatty white substance that covers axons
- no myelin sheathing in brain
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neurilemma
- generates nerve cells in PNS
- none in CNS
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neuoglial cells
- support cells for neurons
- produce CSF
- can cause gliomas (brain tumors)
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neuromuscular junction
junction between ends of large myelinated nerve fiber and skeletal muscle
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acetylcholine
neurotransmitter that speeds transmission of impulses
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cholinesterase
neurotransmitter that deactivates acetylcholine
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norepinephrine
neurotransmitter regulates mood, dreaming, arousal from sleep
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dopamine
neurotransmitter that affects motor function to depress neuron speed (also effects mood)
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serotonin
neurotransmitter that induces sleep and affects mood, sensory perception, and temperature
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cerebrum
- largest portion of the brain
- four lobes:
- --frontal
- --parietal - top
- --occipital - back
- --temporal - sides
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corpus callosum
connects left and right hemispheres of the cerebrum
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pyrmidal motor tracts
travel from motor cortex to spine
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extrapyramidal motor tracts
tracts do not meet with spine / only affect brain tissue
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basal ganglia
- located deep within brain
- responsible for fine motor movements of hands and lower extremities
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frontal lobe
- high level cognitive functions
- memory
- voluntary movement (opposite side of body)
- respirations, GI, BP
- speech
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frontal lobe damage
- paralysis
- memory loss
- inflexible thinking
- mood changes
- difficulty with problem solving
- inability to express language
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Broca's area
responsible for interpretive areas of speech
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parietal lobe
- vision / touch
- integration of different senses
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parietal lobe damage
- inability to multitask
- inability to write (agraphia)
- inability to read (alexia)
- diffuiculty with math (dyscalculia)
- lack of eye hand coordination
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occipital lobe
primarily responsible for vision
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occipital lobe damage
- visual field cuts
- difficulty identifying colors
- drawing, reading, writing
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temporal lobe damage
- difficulty understanding words
- increased interest in sexual behavior
- aggressive behavior
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Wernicke's area
involved in the understanding of written and spoken language
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diencephalon
- contains hypothalamus / thalamus
- lies beneath the cerebrum
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hypothalamus
controls body temp, fluid balance, appetite, certain emotions, sympathetic/parasympathetic systems, and pituitary
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thalamus
- lies above the hypothalamus
- relays sensory impulses
- interprets pain, light tough, pressure
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cerebellum
- coordinates voluntary movement
- maintains balance, equilibrium, and muscle tone
- semicircular calans send messages to cerebellum
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cerebellum damage
- loss of fine motor control / walking
- vertigo
- slurred speech
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brainstem
- connects spinal cord to cerebrum
- 3 parts:
- --midbrain
- --pons
- --medulla oblongata
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midbrain
- motor movement
- relays impulses
- auditory/visual reflexes
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pons
- connects midbrain to medulla
- controls respirations
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medulla
controls heartbeat, breathing rhythm, swallowing, coughing, sneezing, vomiting, hiccups, BP
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brainstem damage
- decreased vital capacity (breathing)
- dysphagia
- autonomic nervous system activation
- sleep / alertness disruption
- balance
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CNS protective layers
- dura mater
- arachnoid membrane
- pia mater
- epidural - above dural layer
- subdural - below dural layer
- subarachnoid - below arachnoid layer
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epidural bleeds
more dangerous because epidural layer is supplied by middle meningeal artery (not a vein)
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ventricles
- four cavities in the brain
- contain choroid plexus - manufactures CSF
- cushions brain
- provides nutrients / removes waste
- contanes glucose, urea, salts
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CSF
- circulates in a closed system (brain and spinal cord)
- damage that drains CSF causes build up on the brain (hydrocephalus)
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cerebral circulation
- brain uses 20% of O2 and 750ml/min of blood
- arterial blood supplied through internal carotids / vertebral arteries
- travels through circle of Willis
- drains via jugulars
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spinal cord
- 17-18" cord
- extends from brainstem to 2nd lumbar vertebra
- conducts impulses to/from brain
- controls reflex actions
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dermatomes
each spinal cord nerve root innervates a specific area of the body
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peripheral nervous system
- motor nerves
- sensory nerves
- ganglia outside brain
- spinal nerves (31 pairs)
- cranial nerves (12 pairs)
- autonomic nervous system
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spinal nerves
- 31 pairs
- mixed (sensory, motor, both)
- named and numbered by corresponding vertebra
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cranial nerves
- 12 pairs
- attach to brainstem
- conduct impulses between head, neck, and brain except Vagus (thoracic and abdominal cavities)
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autonomic nervous system
- maintains homeostasis
- sympathetic & parasympathetic
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sympathetic nervous system
- fight or flight
- increased HR, BP, adrenal secretions
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sympathetic neurotransmitters
- known as catecholamines
- epinephrine
- norepinephrine
- dopamine
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adrenergics / sympathomimetics
meds that mimic sympathetic nervous system
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parasympathetic nervous system
slows system (opposite of sympathetic)
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parasympatheic neurotransmitter
acetylcholine
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cholinergics / parasympathomimetics
drugs that mimic parasympathetic nervous system
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