1350: Immunity EXAM 3

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  1. What are some functions of the immune system?
    Protects from infection.

    Removes and destroys dead/damaged cells.

    Identifies/destroys malignant cells.
  2. When does pathophysiology occur?
    When the body does not recognize "self" from "non-self".
  3. Immune function.

    Describe differences between Natural (innate) Immunity versus Acquired (adaptive) immunity.
    WBC action: releases cell mediators such as histamine, bradykinin, and prostaglandins, and engulf foreign substances.

    Inflammatory response

    Intact skin, chemical barriers, and acidic gastric secretions or enzymes in tears & saliva.
  4. What is the difference between Active and Passive immunity?
  5. What are the 3 defenses of the immune system?
    • Phagocytic immune response
    • Humoral or Ab response
    • Cellular immune response
  6. Comparison of Humoral (B cells) and Cellular (T cells) Immune responses.

    What are some Humoral (B cell) responses to immunity?
    • Humoral (B cells): 
    • phagocytosis
    • anaphylaxis
    • allergic hay fever and asthma
    • immune complex disease
    • bacterial and some viral infections
  7. Comparison of Humoral (B cells) and Cellular (T cells) Immune responses.

    What are some Cellular (T cell) immune responses?
    • Cellular (T cells):
    • transplant rejection
    • delayed hypersensitivity
    • Graft-vs-Host disease
    • tumor destruction
    • viral, fungal, parisitic infections
  8. Which immunity is inherited from birth?
    Nonspecific/innate/natural immunity.
  9. Which type of immunity is received after birth?

    What two types of immunity does this immunity divide into? Give an example.

    Active: defenses developed by self.

    Passive: developed from sources outside of the body such as via breast-feeding.
  10. What are some immune modulators and their functions (treatments)?
    interferons: antiviral & antitumor properties to treat MS and chronic hepatitis.

    Colony: regulates growth & differentiation of bone marrow cells.

    Monoclonal Abo: growth and production of Abo for specific pathologic organisms.
  11. Lab studies. What are the normal values?

    • Hgb: 12-16 g/dl
    • Hct: 33-51%
    • Platelets: 140k-440k /mL blood
    • WBCs: 4.5k - 10k /mL blood
  12. Health history. What should you include in the health history?
    • nutrition
    • immunications
    • allergies
    • autoimmune disorders
    • cancer
    • chronic illness
    • meds
  13. What should you include in the physical examination?
    • general appearance
    • VS
    • mucous membranes
    • skin color, moisture, temp. intactness
    • inspect and palpate lymph nodes
    • assess musculoskeletal system
    • join ROM
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1350: Immunity EXAM 3
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