Staph and strep species
Key lesion: bullae
- caused by?
Group A Beta-hemolytic strep
lesions: Scarletina and cardiac vgetations (abnormal growth of the heart)
Toxic Shock Syndrome
lesions: Scarletina/ thickening of the lips
Scalded Skin Syndrome
S. aureus and other staph species
Scalded Skin toxin
caused by which bacteria?
mixed petechail and macropapular rash
generally on extremities and flexor surfaces
Rocky Mountain Spotted Fever
- borne from
obligate intracellular parasite
- three classifications
- Mycobacterium leprae
- three classifications: lepromatous, tuberculoid, borderline
- causes what?
- Bacillus anthracis
- normally causes a nondescript pneumonia
extreme lesions: eschars
- - Factor I: edema factor (EF)
- - Factor II: protective antigen (PA)
- - Factor III: lethal factor (LF)
- Borrelia burgdorferi
- Arthropod bourne
- Erythemia chronica migrans (chronic migrating redness)
- bullseye rash
bilateral inflammation fo the eyelid
acute infection of the glands of the eye follicle
infection of the Meibomian glands of the eyelid
Botulism and Tetanus
- both caused by which bacterium
- botulism results in?
- tetanus results in?
- Clostridium species
botulism: food poisoning, soil; "floppy babies"
tetanus: spastic muscle contractions
--> caused by
--> associates with
--> infectious factor?
- --> Caused by Bordetella pertussis
- --> associates with ciliated respiratory epithelium
- --> incubation in healthy patients is 5 to 14 days
- --> cough begins during the catarrhal stage and becomes paroxysmal
- --> pertussis is highly contagious, 20-47% of those exposed develop infection
the bacteria produces multiple toxins
- - hemaglutinin attaches the organism to ciliated cells of the upper resp. tract
- - the tracheal cytotoxin stops cilia movement and eventually kills the ciliated cells
- - the dermonecrotic toxin constricts the local and peripheral blood vessels
- ( results in localized tissue and skin necrosis)
- what forms?
- M. tuberculosis
- Ghon complex
- C. diptheriae
- up to 1920, killed upwards of 150, 000 people per year in the US
- common lesion: bullneck
Bubonic and Pneumonic plague
- caused by?
- characteristic appearance?
- called what?
- what forms?
safety pin appearance
The Black Death
entry (bite of infected rat flea)
spread through lymphatic and systemic system
- disease (bubos)= black hemorrhagic lymph nodes
- Exits (highly contagious)
- 1) entry
- 2) disease (pneumonia; usually 100% mortality)
- 3) exit (highly contagious)
- caused by which bacteria?
- what does it cause?
caused by Vibrio cholerae
- - early on, fecal and malodorous
- - later, "rice water stool"
- - painless, non-straining, massive
Another symptom of cholera
- - massive diarrhea--more than 1/5 the entire body weight
- - sunken eyes and cheeks
- - slow "pinch response"
- - rapid and weak or missing pulse
- Death can occur in less than 12 hours
- Cholera cot
Pathway of cholera
- entry via the mouth
- colonization in the colon
- disease (hypovolemic shock, acidosis, vomiting, diarrhea, muscle cramps)
- infectious factor?
- caused by Neisseria gonorrhoeae
- painful urination
- copious amounts of pus
- can be transferred to a child during birth
- caused by __
- how many stages?
primary, secondary, tertiary, congenital
Deformed nasal bridge
Hutchinson's (notched) teeth