The flashcards below were created by user
jeremygregory25
on FreezingBlue Flashcards.
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What is a NMJ
Interference of a motor neuron terminals with muscle fibers
Ach causes sodium/calcium entry through nicotinic muscarinic receptors, and is at every single NMJ
activte actin/myosin
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What neurotransmitter and receptors mediate movement
The Basal Ganglia System
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where are motor nerve somas
In the brainstem
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What does the spinal cord mediate
controls skeletal muscles in response to sensory information (controls voluntary movement)
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What is the pyramidal system?
axons from motor neurons in cortex, down brainstem/medulla pyramids, to spinal cord (corticospinal tract), to motor neurons in ventral horns
they all synapse at the ventral horns
most neurons send axon out ventral roots to muscles
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What 3 areas of cortex mediate movement?
Precentral Gyrus (M1), premotor cortex, SMA
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What 3 areas are considered the extrapyramidal system? (basal Ganglia)
(control/inhibition)
interconnecting modulating movements
mediates direction of movement, initiation of movement, movements learned (contrast to movement due to sensation)
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What 3 areas are considered the extrapyramidal system? (Cerebellum)
modulates movement, error detection
guides movement by inhibition (motor/non-motor learning)
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What 3 areas are considered the extrapyramidal system? (Brainstem nuclei)
reticular formation, red nucleus
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What is the Biology underlying some motor disease
ALS (Lou Gehrig's disease)
motot neuron loss (caudal to rostral progression)
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