Aerobic curved motile Gram-negative bacteria (no axial filament polar filament) Non-motile Gra

• gastroenteritis
• --> causes a lot of diarhea, highly infectious
• --> fecal oral spread
• --> sometimes, a hemmorhage in the GI tract forms
• --> can cause protein and fluid loss

• duodenal ulcers that are infectious
• five species that differ on genetic analysis

a few saprophytes; a lot of bacteria that cause problems with living platnts

opportunistic

• P. aerogenosa: common skin inhabitant that produces toxin on a cut, giving green hue
• problems with people burned 60-70% of their body 
• has a capsule like structure that is not affected by immune system

plant stem and root tumors

• cause large growth on stem of plant. Reduction of xylen and phloem of plant. Rots and plant dies.
• some tumors on roots--> water not getting through--> weakening

• Whooping cough
• great bacteria
• very little variety in terms of genetics so that every vaccine against it is really effective
• highly infectious and causes serious problems for three reasons: 
• 1) sticks to respiratory lining (glycocalyx and fimbriae that sticks to it)
• 2) for resp cells that are ciliated, it paralyzes cilia; things that get down stay down because of this
• 3) if its not bad in respiratory tract, it secretes potent cytotoxin; secreted by cell--> kills cell that bacterial cell is associated with; then, it continues to randomly destroy cells (mechanism works by shutting down protein synthesis)

• Legionaire's disease: fancy bacterial pneumonia
• described in 1976
• bacterium causes pneumonia
• rapid onset
• a heavy dose differentiates it from other pneumonia and a dose that happens repeatedly
• static populations get this today
• in nursing homes, geriatric facilities, due to immobile individuals sitting under vent getting exposed
• this bacteria is in ACs
• specific humidity range

• gonorrhea
• bacteria can secrete enzymes that allow them to get through mucous membranes so bacteria can set up infection
• immune system tries to get rid of it, but it has a series of proteins that allow it to live in a lysozome; can live and thrive
• deregulates it so it is not an effective WBC; won't attack bacteria

bacteria are highly immunogenic. It makes immunity against it

reinfection can occur as much as possible

• E.coli: digest and break down material in gut; can activate certain drugs
• once cell type you have the most of is e. coli
• toxins: ST toxin and CT toxin

ST toxin: very effective colonizers of GI tract--> diarrhea--> hemmorage--> die

facultative anaerobes

• opportunistic pneumonia and bacteremia
• exceedingly rare in individual who are not homeless, IV users, etc.

• peritrichous: urinary tract infections, pimple (domydomes) 
• rapidly moves in moist tissue

• typhoid fever
• respiratory tract disease with high cyclic fevers
• run through large number of those living in close proximity
• one of the diseases that has asymptomatic carriers (can carry but never get)

• one prob: fecal oral spread-> unique toxins that lead to fluid loss, diarrhea, etc. 
• have cytotoxins that can lead to hemmorhage
• bloody diarrhea
• strain determines success of survival

• opportunistic; mastitis in cows
• infections in utters

dysentery

dysentery

• bubonic plague is somewhat common
• most commonly associated with rats and mice and fleas
• bacteria in through bite of flea or rodent--> travels through body and fever, systemic infection, major diarrhea, fluid buildup in limbs--> hyperactive lymph nodes

bubo: hyperactive lymph node; once it shows up, you can't fix it

can be aerosilized

pneumonic play of disease= 100% death

bacteria ends up in GI tract with acids, etc. 

people throw up bile and blood

Vibrio cholerae: cholera

• small check shaped; oral spread
• readily treated with IV and antibiotics

caught early--> survival rates= 90%

• secretes potent toxins
• --> water goes out of body
• --> individuals with this can lose up to 20% of body weight
• --> only a problem if treatment isn't sought
• --> no real digestive effect

protein rich metabolism--> rice water stool

• treatment--> recovery
• no treatment--> dehydration (water comes out from everywhere); weird products in the blood

die from dehydration

in general can break down tissue effectively

once in CNS--> rapid infection

takes immune system a long time to deal with it

• soft chacroid (a venereal disease)
• infectious STD: small cankers on genitalia (soft crankoids; large)
• causes disease that is not transmitted
• common in children and caused by contact

causes nonsexually trasmitted ulcerative lesions in children as well (no sexual contact but may have gotten a cut on the leg or came in contact with someone with it)