Spirochaetes family

  1. Treponema pallidum
    - what does it do in terms of embranes.
    • crosses over thin mucous membrane or epithelial layer; cankers form
    • causes syphilis
  2. Three phases to syphilis
    • 1) canker sores
    • 2) second form: syphilids 
    • 3) non-infectious: 3 unique lesions
  3. 1) Canker sore
    3-6 wks post exposure; antibiotics--> disease clears up (you'll see)

    only at primary site of inoculation
  4. 2) Syphilids
    • a small percentage don't get the drugs they need--> secondary form can show up 8-12 years later.
    • Not as infectious as primary and get lesions around the body called syphilids, which can be systemic
  5. 3) Non-infectious 

    ----> dermatologic
    • three unique lesions; occurs in people who are constantly infected or do not get treatment; they are not infectious
    • 1) dermatologic: large, shallow, nonhealing wounds (gumma= small, non cancerous growths); shallow, bleed a bit; located on tthe surfaces of long bones where there isn't much connective tissue
  6. 3) Non-infectious 

    ----> neurosyphilis
    2) neurosyphilis: small foci of necrosis in the brain--> fluid filled cysts and give person dementia (symptoms similar to Alz); because of degeneration of brain
  7. 3) Non-infectious 

    ----> cardiosyphilis
    • teasing aneurysms of great vessels
    • all nice muscle cells and everything keeping BV intact teases away--> thin spot--> ballooning

    gets so large that it works like a fist-like structure; projects in front of heart--> balloon pops under pressure--> bleed to death
  8. Syphilis bacterium is a __. It needs to be active during the __. It can do what?
    • teratogen (agents that induce birth defects)
    • first trimester
    • cross barriers that others can't. Causes changes on developmental processes

    • Cat's eye cataract
    • deformed nasal bridge
    • Hutchinson's teeth
    • Disabored skin
  9. cat's eye cataract
    thick scarring of the lens--> completeyl opaque--> blind
  10. deformed nasal bridge
    • nose sunken in
    • can also be absent
  11. Hutchinson's teeth
    knotches in teh front teeth
  12. Sabre shin
    one leg is noticeably bowed; causes one shorter leg
  13. Borellia burgdorferi
    • tick bite--> Lyme's disease
    • lives in bacterial glands
    • injects a coagulant
    • classic lesion (one lesion unique and distinctive)--> Bull's eye rash (very characteristic)
  14. Borellia burgdorferi

    - People who don't get diagnosed
    premature arthritis, fatigue syndromes like chronic fatigue syndromes
Card Set
Spirochaetes family
Test Two