Cell Biology 4 - Lysosomes

  1. What are heterophagy and autophagy?
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  2. What are lysosomes?
    Lysosome (derived from the Greek words lysis, meaning "to loosen", and soma, "body") is a membrane-bound cell organelle found in animal cells (they are absent in red blood cells).

    They are structurally and chemically spherical vesicles containing hydrolitic enzymes, which are capable of breaking down virtually all kinds of biomolecules, including proteins,nucleic acids, carbohydrates, lipids, and cellular debris.

    They are known to contain more than fifty different enzymes which are all active at an acidic environment of about pH 5.

    Thus they act as waste disposal system of the cell by digesting unwanted materials in the cytoplasm, both from outside of the cell and obsolete components inside the cell.
  3. How is an acidic lysosomal pH maintained?
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  4. What are lysosomal enzymes, and how are they synthesized and packaged?
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  5. What is I-cell disease?
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  6. What is the endosomal-lysosomal system?
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  7. What is phagocytosis?
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  8. How are some pathogens able to evade phagocytic destruction?
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  9. What is receptor-mediated endocytosis?
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  10. How is cholesterol transported?
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  11. How is iron transported?
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  12. What is an early endosome used for?
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  13. What happens to signalling receptors?
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  14. How do viruses exploit receptor mediated endocytosis?
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  15. What is pinocytosis?
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  16. What is autophagy?
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  17. Describe a picture of the roles of lysosomes in cellular processing.
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  18. What are lysosomal storage diseases?
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  19. What is tay-sachs disease?
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  20. Give a summary of lysosomes and cellular processing
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Card Set
Cell Biology 4 - Lysosomes
Cell Biology 4 - Lysosomes