Lymphtic system chap 21

  1. First line of defense.
    Intact skin and mucous membranes
  2. Second line of defense
    Inflammatory response
  3. Third line of defense
    Immune response
  4. Innate defense system.
    Inflammatory response and skin and mucous membranes
  5. Adaptive defense system
    Immune response
  6. Small proteins secreted by virus‐containing cells.
    A)  Interferon
  7. Major innate mechanism that mediates destruction of foreign substances in the body.
    B)  Complement
  8. Stimulate the proliferation of other lymphocytes.
    C)  Helper T cells
  9. Dampen the activity of both T cells and B cells
    Regulatory T cells
  10. Present the double activation signal to T cells.
  11. Main antibody of both primary and secondary immune response.
    A)  IgG
  12. Protects mucosal barriers.
  13. Involved in allergies
  14. Along with IgM, this is a B cell receptor.
  15. Activates complement.
  16. A graft from a monkey to a human is an example of an allograft. TF
  17. The mechanism of the "lethal hit" of cytotoxic T cells and NK cells involves a protein called perforin. TF
  18. Cellular ingestion and destruction of particulate matter is called phagocytosis   TF
  19. The respiratory burst produced by some macrophages releases free radicals.   TF
  20. The directional movement of cells in response to chemicals is called chemotaxis  TF
  21. Substances capable of triggering the adaptive immune system and provoking an immune response are called antigens   TF
  22. Soluble proteins secreted by plasma cells are called antibodies. TF
  23. A given pathogen will provoke either a cell‐mediated response or an antibody‐mediated response but not both TF
  24. Fever is seldom beneficial because it speeds up the cellular metabolic rate and will not allow antigen‐antibody reactions to occur. TF
  25. Monoclonal antibodies can be specific for several antigenic determinants
  26. Both T cells and B cells must accomplish double recognition:  They must simultaneously recognize self and nonself to be activated.
  27. Some immunocompetent cells will never be called to service in our lifetime  TF
  28. Anaphylactic shock can result from an immediate hypersensitivity where the allergen enters the blood.  TF
  29. Adaptive immunity is provided only by lymphocytes that secrete antibodies.
  30. A transfusion reaction is a subacute hypersensitivity to foreign red blood cells TF
  31. Somatic recombination by B cells allows each B cell to form its own unique antibody genes. TF
  32. Antigens can be complete or incomplete TF
  33. It is our genes, not antigens, that determine what specific foreign  substances our immune system will be able to recognize and resist.  TF
  34. Which of the following is characteristic of antibodies?

    C)   composed of heavy and light polypeptide chains 0
  35. Which of the following is associated with passive immunity?
    A)  booster shot of vaccine
    B)  exposure to an antigen
    C)  passage of IgG antibodies from a pregnant mother to her fetus
    D)  infusion of weakened viruses
    C)  passage of IgG antibodies from a pregnant mother to her fetus
  36. Which of the following is not a type of T cell?  

    D)   antigenic
  37. B lymphocytes develop immunocompetence in the

    A)   bone marrow
  38. Which of the following is not a function of the inflammatory response?
    A)  sets the stage for repair processes
    B)  replaces injured tissues with connective tissue
    C)  prevents the spread of the injurious agent to nearby tissue
    D)  disposes of cellular debris and pathogens
    B)  replaces injured tissues with connective tissue
  39. The redness and heat of an inflamed area are due to a local hyperemia caused by ________.

    B)   vasodilation
  40. The antibody molecule is held together by ________ bonds.

    B)   disulfide
  41. In clonal selection of B cells, which substance is responsible for determining which cells will eventually become cloned?

    A)   antigen
  42. Which of the following statements regarding NK cells is a false or incorrect statement? 

    C)   NK cells are a type of neutrophil.
  43. The process whereby neutrophils and other white blood cells are attracted to an inflammatory site is called

    B)   chemotaxis
  44. Small molecules that bind with self‐proteins to produce antigenic substances are called
    A)  ions 
    B)  reagins
    C)  haptens 
    D)  antibodies
    C)  haptens
  45. Which of the following is the correct sequence of events in phagocytosis?

    B)   chemotaxis, adherence, ingestion, digestion, killing
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Lymphtic system chap 21