Cell Biology 2 - Medically Relevant Viruses

  1. What is the structure of the Virion?
    Naked and Enveloped?
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  2. What is the replication cycle of a bacteriophage?
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  3. How does adsorption and penetration by a bacteriophage work?
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  4. How can a virus infect a cell?
    A virus can only infect a cell if it can interact with a specific receptor on its plasma membrane.

    The presence of receptors delimits the virus host range

    The receptor is a normal surface protein or lipid component of the host cell, often involved in cell-cell recognition and the immune system.

    Animal viruses enter by receptor-mediated endocytosis or by membrane fusion.
  5. How do viruses enter cells by receptor-meditated endocytosis?
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  6. How do viruses enter by membrane fusion?
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  7. What is the time course of events in T4 phage infection?
    What are early viral proteins and what are late viral proteins?
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  8. How are viruses categorised?
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  9. How do class 1 viruses replicate: ds DNA Genome?
    The host cell enzymes transcribe the viral DNA into mRNA and translate viral proteins.

    Virally-encoded DNA polymerase then replicates the viral genome

    Animal Viruses: Adenovirus Papillomavirus, Herpes Virus
  10. What type of virus is Adenovirus?
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  11. What type of virus is Herpesvirus?
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  12. How do Class IV viruses replicate? - ss plus strand RNA genome?
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  13. What is poliovirus and how does it replicate?
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  14. How do class V viruses replicate? ss minus strand RNA genome
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  15. How is rabies virus replicated?
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  16. What is influenza virus, and how does it replicate?
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  17. How do Class VI viruses replicate? ss + RNA genome that replicates with a DNA intermediate
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  18. What is the structure of a retrovirus?
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  19. How does HIV-1 enter a cell and then replicate?
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  20. What effects can animal viruses have on host cells?
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  21. What should you think about when thinking about viral replication?
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  22. How are viruses assembled once why have replicated?
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Card Set
Cell Biology 2 - Medically Relevant Viruses
Cell Biology 2 - Medically Relevant Viruses