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Functional Class
Loop Diuretic
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Mechanism of Action
- Rapid-acting, potent
- Inhibits sodium and chloride reabsorption in the nephron's loop of Henle.
- Vasodilatory properties reduce preload
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Contraindications
- Hypersensitivity
- Hypotension
- Dehydration
- Electrolyte depletion
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Precautions
- Usage in pregnancy should be limited to life threatening situations as furosemide may cause fetal abnormalities
- Renal or hepatic insufficiencies
- Protect from light
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Side Effects
- Hypotension
- Dizziness
- CP
- Dry mouth
- Hypochloremia
- Hypokalemia
- Hyponatremia
- Hypomagnesemia
- Hypocalcemia
- N/V
- Ototoxicity
- Hyperglycemia
- Tinnitus if pushed to rapidly
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Interactions
- Digitalis
- Lithium toxicity
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Dose and Route
- 0.5-1 mg/kg slow IVP over 1-2 mins
- General dosing is 40-120 mg slow IVP
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