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Major ORGANIC component of urine
Urea
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Major INORGANIC component of urine
Chloride
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Second Major INORGANIC component of Urine
Sodium
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Third Major INORGANIC component of Urine
Potassium
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Non dissolved substances found in Urine
- Bacteria
- Crystals
- Casts
- Mucus
- RBC
- WBC
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two-bean shaped organs located under the diaphragm on either side of the aorta in the posterior upper abdominal region
Kidney
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Where is the Kidneys located?
a. Above or under the Diaphragm?
b. What side of the Aorta?
c. What part of the abdominal region?
- a. Under the Diaphragm
- b. Either Side of the Aorta
- c. Posterior Upper Abdominal Region
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A muscular tube that connects the pelvis of the kidney to the bladder
Ureter
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Where is Urine Excreted?
Urethra
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A cavity area that is an expansion of the ureter
Renal Pelvis
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It functions to collect urine from the calyces for transport from the kidney to the ureter
Renal Pelvis
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Region of Kidney comprising the Outer Layer
Cortex
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Region of Kidney comprising the Inner Layer
Medulla
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It is comprised of renal corpuscles and the proximal and distal convoluted tubules of the nephron
Cortex
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Comprised of the Loop of Henle and collecting ducts
Medulla
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Where are the loops of Henle and collecting ducts found?
Medulla, specifically in the Tubular System
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Where are the renal corpuscles found?
Cortex
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Where are the proximal and distal convoluted tubules found?
Cortex, specifically in the Tubular System
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Where are the collecting ducts found?
Medulla
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It supplies blood to the renal artery
Abdominal Aorta
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It provides blood to the kidneys and the renal vein
Renal Artery
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It functions to return blood to the inferior vena cava (found in the kidneys)
Renal Vein
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Functional Unit of the Kidney
Nephron
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Comprised of the Renal Corpuscle and a tubular system that is responsible for the formation of Urine
Nephron
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It consists of the glomerulus and Bowman's Capsule
Renal Corpuscle
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It consists of the Proximal Convoluted Tubule, Loop of Henle, Distal Convoluted Tubule and collecting duct
Tubular System
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Where is the Glomerulus found?
Renal Corpuscle or Tubular System?
Renal Corpuscle
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Where is the Bowman's capsule found?
Renal Corpuscle or Tubular System?
Renal Corpuscle
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A tuft of capillaries that lie in a tubular depression
Glomerulus
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A tubular depression where the glomerulus lies
Bowman's Capsule
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It carries blood into the glomerulus
Afferent Arteriole
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It carries blood away from the glomerulus
Efferent Arteriole
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They aid in the tubular reabsorption process by surrounding the various segments of the renal tubule
Peritubular Capillaries
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Where do Peritubular capillaries arise from?
Afferent or Efferent Arteriole?
Efferent Arteriole
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It primarily functions to filter blood
Glomerulus
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Where does the Loop of Henle begin and end? and where is it mainly located?
Cortex, but it is mainly located at the Medulla
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It directs the urine flow into the collecting duct.
Distal Convoluted Tubule
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What is the Papillary duct made of?
Collecting Ducts
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It carries urine into a calyx of the renal pelvis
Papillary Duct
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Three processes that function together to form excrete urine
- Glomerular Filtration
- Tubular Reabsorption
- Tubular Secretion
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It functions as a semipermeable membrane to make an ultrafiltrate of plasma that is protein free
Glomerulus
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What might be damaged if protein is found in the urine?
Glomerulus
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Where to large molecules (proteins) stay as the glomerulus filters the blood?
Arterioles
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What is the Glomerular Filtration Rate?
115ml-125mL/min
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They reabsorb all but 1mL of the Glomerular Filtrate
Renal Tubules
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The passageway when filtered water, ions, and molecules return to the blood
Peritubular Capillaries
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Responsible for approx. 65% of the reabsorption and secretion that occurs in the renal tubules
Proximal Convoluted Tubules
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The limitation as to how much solute can be reabsorbed
Renal Threshold
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What is the Renal Threshold (amount)?
160-180 mg/dL
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Part of the Loop of Henle that reabsorbs water
Descending Loop of Henle
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Part of Loop of Henle that reabsorbs Sodium and Chloride
Ascending Loop of Henle
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Where does the filtrate go after reabsorption occurs in the Loop of Henle?
Distal Convoluted Tubule
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How much reabsorption occurs in the Loop of Henle?
approx 85% reabsorption of water and salt
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What is reabsorbed in the distal convoluted tubule?
- Only Sodium and Water
- Note: Chloride not reabsorbed
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Controls the reabsorption of water in the Distal Convoluted Tubule
Anti-Diuretic Hormone (ADH)
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Enzyme that controls the reabsorption of sodium and water and secretion of potassium and hydrogen into the filtrate
Aldosterone
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Final site for water reabsorption
Collecting Duct
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It is secreted by the juxtaglomerular apparatus of the kideys and catalyzes the conversion of angiotensinogen to angiotensin I
Renin
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Structure that secretes Renin
Juxtaglomerular Apparatus of the kidneys
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What is converted by Renin?
Angiotensinogen is converted to Angiotensin I
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It stimulates the production of Angiotensin II
Angiotensin I
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Which is the active and inactive form?
Angiotensin I or II?
- Active Form = II
- Inactive = I
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It regulates the renal blood by constricting the renal arterioles and secreting aldosterone from the adrenal glands to facilitate retention of sodium
Angiotensin II
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Where is Aldosterone made?
Cortex of the Adrenal Glands
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Where is Anti-Diuretic Hormone (ADH) secreted?
Posterior Pituitary Gland
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What parts of the Kidney does the anti-diuretic hormone primarily affect?
- Distal Convoluted Tubule
- Collecting Duct
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It promotes calcium reabsorption from the filtrate into the blood and excretion of phosphate ions from the blood into the filtrate
Parathyroid Hormone (PTH)
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Where are the Parathyroid Hormone (PTH) made?
Parathyroid Glands
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An alpha-globulin produced by the peritubular fibroblasts in the kidneys to stimulate red blood cell production in response to lowered oxygen levels
Erythropoietin
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inflammation of the glomerulus characterized by hematuria, proteinuria, WBCs, and casts, but does not result in Renal Failure
Acute Glomerulonephritis
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Type of infection that is followed by acute glomerulonephritis
Group A Streptococcus Respiratory Infection
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inflammation of the glomerulus characterized by hematuria, proteinuria, WBCs, and casts, and may result to renal failure
Rapidly Progressive Glomerulonephritis
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Inflammation of the Renal Interstitium that may be caused by an allergic reaction to medication; characterized by hematuria, proteinuria, WBCs (esp eosinophils) and WBC casts
Acute Interstitial Nephritis
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Usual cause of Acute Interstitial Nephritis
Allergy Reaction to Medication
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Thickening of the Glomerular Capillary Walls and basement membrane; characterized by proteinuria and hematuria
Membranous Glomerulonephritis
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It may be caused by Renal Blood Pressure Irregularities; characterized by proteinuria, hematuria, lipiduria, oval fat bodies, renal tubular epithelial cells, and epithelial cell-, fatty- and waxy casts
Nephrotic Syndrome
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