-
5' cap
a methylated guanine nucleotide added to the 5' end of eukaryotic mRNA. The cap is necessary to initiate translation of the mRNA.
-
"A" band
the band of the sarcomere that extends the full length of the think filament.
-
Absolute refractory period
a period of time following an action potential during which no additional action potential can be evoked regardless of the level of stimulation
-
Accessory glands
- the 3 glands of the male reproductive system that produce semen:
- seminal vesicles, prostate, and bulbourethral glands
-
GI accessory organs
liver, gallbladder, pancreas, salivary glands
-
acetyl-CoA
the first substrate in the Krebs cycle, produced primarily from the oxidation of pyruvate by the pyruvate dehydrogenase complex.
-
acinar cells
cells that make up exocrine glands, and that secrete their products into ducts
-
acrosome
a region at the head of a sperm cell that contains digestive enzymes which, when released during the acrosome reaction, can facilitate penetration of the corona radiata of the oocyte and fertilization
-
actin
a contractile protein. In skeletal and cardiac muscle, it polymerizes to form the thin filaments
-
adenine
On of the four aromatic bases found in DNA and RNA. It is a purine and pairs with thymine (DNA) and uracil (RNA)
-
adrenal medulla
releases epinephrine and norepinephrine
-
afferent artiole
the small artery that carries blood toward the capillaries of the glomerulus
-
albumin
produced by the liver to help maintain blood osmotic pressure
-
amino acid acceptor site
the 3' end of a tRNA molecule that binds an amino acid
-
aminoacyl tRNA
a tRNA with an amino acid attached; made by an aminoacyl-tRNA synthetase
-
amylase
an enzyme that digests starch into disaccharides. Secreted by salivary glands and pancreas
-
androgens
male sex hormones
-
antidiuretic hormone
aka "vasopressin", is produced by the hypothalamus and secreted by the posterior pituitary. Targets the kidney tubules to increase their permeability to water and thus increase water retention
-
the A-site
Aminoacyl-tRNA site; the site on a ribosome where a new amino acid is added to a growing peptide
-
auxotroph
a bacterium that cannot survive on minimal medium(glucose alone), because they cannot synthesize a molecule needed to live
-
bacillus
rod-like shaped bacteria
-
Blotting
the transfer of DNA or proteins from an electrophoresis gel to a nitrocellulose filter
-
Bohr effect
the tendency of certain factors to stabilize hemoglobin in the tense conformation, thus reducing its affinity for oxygen and enhancing the release of oxygen to the tissues
-
Bowman's capsule
the region of the nephron that surrounds the glomerulus. It collects the plasma that is filtered from the capillaries in the glomerulus.
-
calmodulin
A cytoplasmic Ca2+ binding protein, important in smooth muscle cells
-
capsid
outer protein coat of a virus
-
carbonic anhydrase
an enzyme in eruthrocytes that catalyzes the conversion of CO2 and H2O into carbonic acid
-
chief cells
pepsinogen-secreting cells found at the bottom of the gastric glands of the stomach
-
cholecystokinin
a hormone secreted by the small intestine in response to the presence of fats. It promotes the release of bile from the gallbladder and pancreatic juices from the pancreas
-
coccus
a round shaped bacteria
-
co-factor
an inorganic molecule that associates non-covalently with an enzyme, and that is required for the proper functioning of the enzyme
-
cooperativity
a type of substrate binding to a multi-active site enzyme, in which the binding of one substrate molecule facilitates the binding of subsequent substrate molecules
-
desmosome
a general cell junction, used primarily for adhesion
-
DNA polymerase
the enzyme that replicates DNA. Eukaryotes have a single version and Prokayotes have 3
-
ectoderm
ultimately forms external structures such as skin, hair, nails, inner lining of mouth and anus, and the nervous sytem
-
efferent arteriole
the small artery that carries blood away from the capillaries of the glomerulus
-
ELISA
a biochemical technique that utilizes antigen-antibody interactions to determine the presence of either antigens of specific immunoglobulins in a sample
-
endoderm
ultimately forms internal structures, such as the inner lining of the GI tract and some glandular organs
-
enterogastrone
a hormone secreted by the small intestine in response to the presence of food.
-
enterokinase
a duodenal enzyme that activates trypsinogen to trypsin
-
epitope
the specific site on an antigenic molecule that binds to a T-cell receptor or to an antibody
-
euchromatic
DNA that is loosely packed around histones. DNA is more accessible to enzymes and can be activated if needed
-
facultative anaerobe
an organism that will use oxygen to produce energy if it is available, and that can ferment if it is not
-
fibrinogen
a blood protein essential to blood clotting
-
gastrin
a hormone released by the G cells of the stomach in the presence of food. Promotes muscular activity of the stomach as well as secretion of hydrochloric acid, pepsinogen, and mucus
-
DNA gyrase
a prokaryotic enzyme used to twist the single circular chromosome of prokaryotes upon itself to form supercoils.
-
Human chorionic gonadotropin
a hormone secreted by the trophoblast cells of a blastocyst that prolongs the life of the corpus luteum, and thus increases the duration and amount of progesterone. This helps to maintain the uterine lining.
-
helicase
enzyme that unwinds the double helix of DNA and separates the DNA strands in preparation of replication
-
hexokinase
enzyme that catalyzes the phosphorylation of glucose to form glucose-6-phosphate in the first step of glycolysis
-
histones
globular proteins that assist in DNA packaging in eukaryotes
-
H zone
the region at the center of an A band of a sarcomere that is made up of myosin only. Gets shorter with muscle contraction
-
I band
the region of a sarcomere made up only of the thin filaments. Alternate with A bands to give striation
-
interleukin
a chemical secreted by a T cell that stimulates activation and proliferation of other immune system cells
-
kinase
an enzyme that transfers a phosphoryl group from ATP to other compounds
-
Kmm
The substrate concentration required to reach 1/2 Vmax
-
Krebs cycle
acetyl-CoA is combined with oxaloacetate to form citric acid. The citric acid is then decarboxylated twice and isomerized to recreate oxaloacetate
-
Law of segregation
states that two alleles of a given gene will be separated from one another during gamete formation
-
ligase
an enzyme that connects two fragments of DNA to make a single fragment. Used during DNA replication
-
lysozyme
an enzyme that lyses bacteria by creating holes in their cell walls
-
macula densa
the cells of the distal tubule at the juxtaglomerular apparatus
-
mesoderm
ultimately forms "middle" structures such as bones, muscles, blood vessels, heart, kidneys,....
-
Okazaki fragments
small fragments of DNA produced on the lagging strand during DNA replication, joined later by DNA ligase to form a complete strand
-
phosphatase
an enzyme that removes a phosphoryl group from a compound
-
phosphofructokinase
enzyme used in third step of glycolysis (main regulatory step). PFK is feeback-inhibited by ATP
-
proximal convoluted tubule
site of most reabsorption in nephron; all filtered nutrients as well as most filtered water is reabsorbed here
-
P-site
- peptidyl-tRNA site;
- site of a ribosome where the growing peptide is found during translation
-
renin
enzyme secreted by juxtaglomerular cells when BP decreases; Renin converts angiotensinogen to angiotensin I
-
respiratory alkalosis
a rise in blod pH due to hyperventilation and a resulting decrease in CO2
-
saprophyte
an organism that feeds of dead plants and animals
-
secretin
hormone secreted by the small intestine in response to low pH. Promotes the release of bicarbonate from the pancreas to act as a buffer
-
S phase
phase of cell cycle during which the genome is replicated
-
spirochete
spiral shaped bacteria
-
topoisomerase
enzyme that cuts one or both strands of DNA to relieve the excess tension caused by the unwinding of the helix by helicase during replication
-
Z lines
the ends of a sarcomere
-
autotroph
uses CO2 as carbon source
-
What structure must all viruses have?
capsid
-
what triggers relaxation of bronchiol smooth muscle
the activation of the sympathetic nervous system
-
what type of gland is the liver
exocrine gland
-
what is pulse pressure?
difference between systolic and diastolic BP
-
what is lactose intolerance due to?
due to the decrease in the level of expression of β-galactosidase
-
calcitonin
secreted in response to high serum Ca2+; it inhibits osteoclast-mediated bone breakdown and increases osteoblast-mediated bone formation
-
parathyroid and calcitriol
both increase bone reabsorption and decrease bone formation
-
where is red marrow?
spongy bone of flat bones
-
role of surfactant
to reduce surface tension
-
when does secondary oocyte become ootid?
after fertilization, before egg and sperm nuclear membranes fuse
-
Southern blotting
allows you to detect the presence of specific sequences within a heterogeneous sample of DNA. Also allows you to isolate and purify target sequences of DNA
-
Northern blotting
same as southern blotting, except that mRNAs are separated via gel electrophoresis instead of DNA
-
Western blotting
allows you to detect the presence of certain proteins with a sample and also serves as a diagnostic tool
|
|