Description: Adenosine is a naturally occurring agent that can “chemically cardiovert” PSVT to a normal sinus rhythm. It has a half-life of 10 seconds and does not cause hypotension.
Indications: Narrow, complex paroxysmal supraventricular tachycardia refractory to vagal maneuvers.
Contraindications: Hypersensitivity, 2nd- and 3rd-degree heart block, sinus node disease, or asthma.
Precautions: It may cause transient dysrhythmias especially asystole, COPD.
Dosage/Route: 6 mg rapidly (over 1 to 2 sec) IV, then flush the line rapidly with saline. If ineffective, 12 mg in 1 to 2 min, may be repeated. Ped: 0.1 mg/kg (over 1 to 2 sec) IV followed by rapid saline flush, then 0.2 mg/kg in 1 to 2 min to max 12 mg.