Alteplase(rTPA, Activase) Dosage
Adult: Total dose is 100mg. Loading dose of 15mg is administered as an IV bolus over 1-2mins. Followed with an infusion of 0.75mg/kg(up to 50mg)IV over 30mins. Then an infusion of 0.5mg/kg(up to 35mg)IV over 60mins. Infusions must be administered via pump and be carefully monitored.
Peds: Not recommended