Proton-Pump Inhibitor (PPI); causes irreversible inhibition of H+/K+ ATPase (proton pump); _|_ gastric acid secretion; Effects persist until new enzyme is synthesized;
For treatement of duodenal and gastric ulcers, erosive esophagitis, GERD (short-term treatment); For long-term treatment of hypersecretory problems.
omeprazole [Prilosec]